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Muscle cramp: Main theories as to aetiology (1990)

Jansen, P. H. P. ; Joosten, E. M. G. ; Vingerhoets, H. M.

Springer

European archives of psychiatry and clinical neuroscience 239 (1990), S. 337-342

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ISSN: 1433-8491

Keywords: Muscle cramp ; Aetiology

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary Historically relevant hypotheses on the pathophysiology of muscle cramp are reviewed. Psychosomatic, static, vascular, myogenic and neural theories are highlighted from a clinician's point of view. Modern neurophysiological research leaves little doubt that true muscle cramp is caused by explosive hyperactivity of motor nerves. Several mechanisms may be involved including spinal disinhibition, abnormal excitability of motor nerve terminals and spreading of muscle contraction by ephaptic transmission or axon reflexes.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01735062

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