ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
Gas chromatography
;
Experimental design
;
Modelling
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary Experimental Design methodology allows the modelling and optimization of the chromatographic separation of similar pesticides (triazine family) by GC and HPLC. The GC separation of simazin and atrazin is well modelled by a first degree equation, involving injected volume, carrier gas pressure and rising oven temperature. The LC is modelled by a second degree equation, depending on injected volume, eluent flow and composition. These calculated models allow easy optimization of the separations, using isoresponse curves.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02269719