ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] In 1970 it was noted1 that the N and lactone C-C=O in BIC could be isosteric with the N and carboxylate COO of an extended (that is fully trans) GABA molecule (zwitterion at physiological pH) and its equivalent (O-C=N) in the agonist muscimol. Alternatively2, a partially folded GABA molecule could ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/256600a0