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Binding of flexible ligands to macromolecules (1975)

BURGEN, A. S. V. ; ROBERTS, G. C. K. ; FEENEY, J.

[s.l.] : Nature Publishing Group

Nature 253 (1975), S. 753-755

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ISSN: 1476-4687

Source: Nature Archives 1869 - 2009

Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics

Notes: [Auszug] The first model is essentially an extension of Fischer's 'lock-and-key' model (Fig. \a) in which only those ligand molecules which collide with the binding site in the correct conformation (and the correct orientation) are assumed to form a stable complex. In this single-step binding, all the ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/253753a0

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