ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] The caspases are a family of intracellular cysteine proteases that display an absolute requirement for aspartic acid at the PI position of their substrates9. ICE (caspase-1) plays a critical role in the production of IL-la and IL-1 (3, as demonstrated with knock-out mice10'11. CPP32 (caspase-3) ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/386619a0