ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] We introduced two short deletions and 13 amino-acid substi-tutions (Fig. 1) in a region of the HIV envelope that is highly conserved between HIV-1 and HIV-2 (refs 6,7). Insertional mutagenesis at this site is known to abrogate CD4 binding4 and the epitopes for two antibodies that inhibit CD4-gpl20 ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/340571a0