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Punctate porokeratotic keratoderma—its occurrence with internal neoplasia (1994)

BIANCHI, L. ; ORLANDI, A. ; IRACI, S. ; [et al.]

Oxford, UK : Blackwell Publishing Ltd

Clinical and experimental dermatology 19 (1994), S. 0

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ISSN: 1365-2230

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Punctate porokeratotic keratoderma (PPK) represents a diffuse involvement of palms and soles by multiple, acuminate keratotic papules and plugs, histologically identified by parakeratotic cornoid lamellae. A possible association between PPK and internal malignancy has been previously noted by Herman in 19732. A patient with a 3-month history of PPK is described in which a bronchial carcinoma was recently diagnosed. This association led us to speculate that PPK could be a sign of internal neoplasia, as already established for other forms of palmoplantar keratoderma. We suggest that the presence of an underlying malignancy must be screened for when a diagnosis of PPK is proposed.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1365-2230.1994.tb01142.x

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