ISSN:
1471-0528
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Concentrations of 6–keto–prostaglandin F1α (6–keto–PGF1α, the stable metabolite of prostacyclin, PGI2) have been measured in amniotic fluid obtained during late pregnancy and labour. Samples taken at amniotomy during spontaneous labour contained a significantly greater concentration of 6–keto–PGF1α than samples taken at amniotomy before the onset of labour (p 〈0.01). There was no correlation between the level of 6–keto–PGF1α, in amniotic fluid before labour and gestational age (p 〉 0 1). It is suggested that prostacyclin may have a functional role in the mechanism of parturition in man.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1471-0528.1979.tb10609.x