Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Anaesthesia
51 (1996), S. 0
ISSN:
1365-2044
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
The thiopentone dose needed for satisfactory induction of anaesthesia was determined in 60 adult patients using a double-blinded study design. No premedication was given. The effect of pretreatment with four different doses of fentanyl on ED50 for thiopentone was determined and compared with a control group not receiving fentanyl. The cardiovascular effects of the combinations were also studied. ED50 for thiopentone was reduced from 4.0 mg kg-1 in the control group to 2.2mg kg-1 in patients receiving fentanyl 5.0 μg kg-1. Only in the group of patients receiving fentanyl 5.0 μg. kg-1 was there no significant change in systolic arterial blood pressure. An increased heart rate was noted in patients induced with thiopentone in combination with fentanyl 0.625 μg kg-1. No adcerse effkcts of thiopentone, fentanyl or the combinations were noted.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2044.1996.tb12611.x
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