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The effect of intravenous clonidine on the forearm circulation (1991)

CARABINE, U. A. ; WRIGHT, P. M. C. ; KEARNEY, E. ; [et al.]

Oxford, UK : Blackwell Publishing Ltd

Anaesthesia 46 (1991), S. 0

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ISSN: 1365-2044

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: The effect of two doses of clonidine on forearm blood flow was compared with an inert treatment using mercury strain gauge venous occlusive plethysmography. In the clonidine treated groups, forearm blood flow was unaffected in the resting state, but decreased sharply with tracheal intubation. In the saline group, blood flow increased with intubation. Forearm vascular resistance increased in the clonidine treated groups, but decreased in the saline group. These results suggest that clonidine has a peripheral action in anaesthetised normotensive individuals, and is not a purely centrally acting drug.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1365-2044.1991.tb09911.x

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