Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Anaesthesia
45 (1990), S. 0
ISSN:
1365-2044
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
One hundred and ten male patients scheduled for coronary artery bypass grafting were allocated randomly into one of three groups. Patients in group A received fentanyl 7 μg/kg via a central venous catheter, those in group B were given fentanyl 7 μg/kg through a peripheral venous cannula, and patients in group C received sterile water via a central venous catheter. In group A, 45.9% of patients coughed after injection of fentanyl; the mean onset time from the end of fentanyl administration to the beginning of coughing was 10.6 seconds. Only one patient in group B and no patient in the control group exhibited a cough response (p 〈 0.0001). We hypothesise that fentanyl can evoke the pulmonary chemoreflex.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2044.1990.tb14496.x
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