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The Non-Specific Enhancement of Allergy I. (1983)

Pauwels, R. ; Straeten, M. Van Der ; Platteau, B. ; [et al.]

Oxford, UK : Blackwell Publishing Ltd

Allergy 38 (1983), S. 0

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ISSN: 1398-9995

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Bordetella pertussis organisms, with or without a small dose of alumhydroxide, enhance in rats the production of IgE antibodies to an unrelated antigen, even if this antigen has been administered 6 weeks beforehand. This non-specific enhancement of IgE antibodies is accompanied by a substantial rise in total serum IgE and by the production of IgE antibodies to B. pertussis. The effect of B. pertussis on IgE synthesis is dose-dependent. No effect of B. pertussis on IgE production can be observed in nude rats.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1398-9995.1983.tb01617.x

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