Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Journal of oral pathology & medicine
25 (1996), S. 0
ISSN:
1600-0714
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
The distribution of T lymphocytes expressing the αβ or γδ heterodimer of the T cell receptor (TCR) was examined in normal oral mucosa (NOM) and reticular oral lichen planus (OLP) using a panel of antibodies specific for CD3, the αβ TCR and the γδ TCR. Intra-epithelial lymphocytes were counted and epithelial surface length was measured by image analysis. T cells in the lamina propria were not quantified. Total intra-epithelial lymphocytes were increased in OLP compared with NOM (p=0.0004). The proportions of cells expressing the γδ TCR in NOM and OLP were 10% and 9.3%, respectively, suggesting there is no selective recruitment from the circulation of either αβ or γδ TCR-bearing cells into normal oral epithelium or that affected by OLP The role. if any, of γδ T cells in the pathogenesis of OLP remains to be determined.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1600-0714.1996.tb01727.x
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