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Digitale Medien

Effect of Ethanol Administration on Striatal D1 and D2 Dopamine Receptors (1988)

Hruska, Robert E.

Oxford, UK : Blackwell Publishing Ltd

Journal of neurochemistry 50 (1988), S. 0

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Details

ISSN: 1471-4159

Quelle: Blackwell Publishing Journal Backfiles 1879-2005

Thema: Medizin

Notizen: Abstract: Chronic in vivo exposure of rats to ethanol in a complete liquid diet for 14 or 21 days produced a behavioral tolerance to the acute injection of ethanol. After 21 days, but not 14 days, of chronic exposure, there was a significant increase in the maximum density of striatal D1 and D2 dopamine receptors without a change in these receptors' affinities. A 24-h withdrawal from the 21-day exposure did not alter the observed increase in density. Both the level and duration of ethanol exposure appear to be important variables for demonstration of an increase in striatal D1 and D2 dopamine receptors.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1111/j.1471-4159.1988.tb02499.x

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