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HPLC Analysis of Neurophysin Proteins from Neurosecretory Granules (1982)

Schwandt, P. ; Richter, W. O. ; Reuschel-Janetschek, E.

Oxford, UK : Blackwell Publishing Ltd

Journal of neurochemistry 39 (1982), S. 0

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ISSN: 1471-4159

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Abstract: Neurosecretory granules were obtained from neurolobes of porcine pituitary glands. From the granules, highly purified neurophysins were prepared by HPLC. According to polyacrylamide gel electrophoresis, isoelectric focusing, N- and C-terminal amino acid residue determination, and amino acid composition, the neurophysins I1 I2, and II were identical to the neurophysins obtained from whole posterior lobes. Since degradation could not have occurred, we conclude that neurophysin I1 and I2 originated in the neurosecretory granules.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1471-4159.1982.tb03955.x

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