Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Journal of neurochemistry
22 (1974), S. 0
ISSN:
1471-4159
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
—The ouabain-sensitive K+ uptake and ATPase activities of cultured glioma and neuroblastoma cells were studied. Both cell lines showed ouabain-sensitive K+ uptake which correlated with the level of [Na++ K+]ATPase activity found in the respective total cell homogenate. The glioma cells had a 2.1-fold higher rate of K+ uptake than neuroblastoma cells, and a 2.4-fold higher [Na++ K+]ATPase activity. In the presence of ouabain neuroblastoma cells released K+ and took up Na+ in a 1:1 ratio. These results are compared and contrasted with similar studies on brain tissue and isolated cells. It is suggested that the cultured cell lines may serve as good models for the cation transport properties of their tissue counterparts.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1471-4159.1974.tb04324.x
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