ISSN:
1600-051X
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Abstract We have estimated the levels of Interleukin-1 beta (IL-1β) by ELISA in gingival crevicular fluid (GCF) at 58 sites from 37 patients with adult periodontitis. GCF was collected for 5 s on filter papers and a 2nd sample was collected for 30 s 1 min later. 68/116 strips yielded detectable levels of IL-1β. IL-1β was present in both the 1 st and 2nd samples at 28 sites, in the 1 st only at 4 sites and in the 2nd only at 8 sites; 18 sites were below the level of detection for the assay. When the concentrations of IL-1β were calculated in the original volume of GCF on each strip, the mean value for positive strips was 34.16±29.45 (SD) pg/μ1 with a range from 1.75 to 97.13 pg/μ. There were no statistically significant correlations with the plaque index, bleeding index or probeable crevice depth (pocket depth). The results indicate that IL-1 is present in the GCF from a proportion of sites with evidence of previous periodontal destruction.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1600-051X.1992.tb01149.x