Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Annals of the New York Academy of Sciences
155 (1969), S. 0
ISSN:
1749-6632
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Natural Sciences in General
Notes:
Histochemical and electron microscopic studies on the nature of the azurophilic hypergranulations of leukocytes in Batten's disease are reported. The exact nature of the phenomenon could not be elucidated, but it appears that the abnormal granulation is due to the prevalence of an intermediate granule in the polymorphonuclear cells. In electron microscopic preparations, the leukocyte granules from patients with Batten's disease are bounded by a unilaminar membrane, in contrast to the trilaminar membrane of the granules in controls. The possibility that this finding may represent a molecular lesion is discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1749-6632.1969.tb50307.x
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