Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Scandinavian journal of immunology
11 (1980), S. 0
ISSN:
1365-3083
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
In an in vitro model system using isolated human granulocytes high molecular weight hyaluronic acid stimulated the initial rate of phagocytosis of complement-opsonized latex particles. This specific quality was dependent on the molecular size and occurred at low concentrations (1–10 mg/1 of hyaluronic acid. However, at high concentrations (〉 100 mg/1) hyaluronic acid inhibited the initial rate of phagocytosis of both IgC- and complement-opsonized particles. The latter effect was shared with chrondoitin sulphate, heparan sulphate and heparin. The results suggest that hyaluronic acid may be instrumental in controlling inflammatory processes.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-3083.1980.tb00034.x
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