Electronic Resource
Oxford, UK; Malden, USA
:
Blackwell Publishing Ltd/Inc.
Journal of cutaneous pathology
32 (2005), S. 0
ISSN:
1600-0560
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
The concept of paracolloid was raised by Dupre et al. in 1979 to describe a rare lesion, in which large amounts of homogeneous, pale pink, non-amyloid material in sun-exposed skin. The deposits consisted of haphazardly arranged microfilaments of 3–4 nm in diameter. Here we report another case. A 54-year-old white male presented with a 2 × 2 cm boggy, erythematous plaque involving the bridge and tip of the nose for two years. The lesion enlarged slowly and intermittently drained pinkish fluid. A shave biopsy revealed extensive homogeneous, pale pink material with fissure and clefts in the dermis. The deposits wrapped up hair follicles and sebaceous glands, and superficially mixed with scattered solar elastic fibers and globules. There were scattered fibroblasts, focal mild perivascular and perifollicular lymphocyte and plasma cells. Adjacent skin showed prominent solar elastosis. A thin grenz zone was present abutting an atrophic epidermis with actinic keratosis. The deposits showed faint Congo red stain with focal weak apple-green birefringence, faint PAS stain, and negative Verhoeff-van Gieson stain. Masson’s trichrome stain and immunohistochemical stain for collagen IV were negative.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.0303-6987.2005.320hn.x
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