Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
FEMS microbiology letters
191 (2000), S. 0
ISSN:
1574-6968
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
Notes:
The bacterial cell division protein FtsZ is a structural analogue of tubulin. Bacterial mutants in which the ftsZ gene is inactivated are unable to divide. Numerous inhibitors of tubulin assembly are known, some of which are used as fungicides. The strong structural homology between FtsZ and tubulin raises the possibility that some of these inhibitors could affect bacterial cell division. Here we report that the tubulin assembly inhibitors thiabendazole and 2-methylbenzimidazole cause cell elongation in Escherichia coli and cyanobacteria.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1574-6968.2000.tb09314.x
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