Electronic Resource
Oxford, UK
:
Blackwell Science Ltd
Journal of the European Academy of Dermatology and Venereology
19 (2005), S. 0
ISSN:
1468-3083
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
The identification of adult epidermal stem cells that are capable of self-renewal and can reconstitute not only the epidermis but also the cutaneous appendages opens new perspectives for the treatment of a variety of human skin disorders including severe burns, cutaneous cancers, alopecia and acne. However, the implementation and improvement of these novel treatment strategies require a better understanding of the biology of stem cells, in particular regarding their isolation and the maintenance of their unique characteristics in culture. In this review, we summarize the main features of epidermal stem cells and we present the most recent advances in our understanding of the development and maintenance of these cells. In addition, we discuss some of the challenges and the potential clinical applications of epidermal stem cell technology.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1468-3083.2005.01279.x
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