Electronic Resource
Oxford, UK
:
Blackwell Science Ltd
Journal of the European Academy of Dermatology and Venereology
15 (2001), S. 0
ISSN:
1468-3083
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
We reported on a case of subcutaneous panniculitis-like T-cell lymphoma (SPTCL) with multiple erythematous nodular lesions on the extremities, trunk and face. Histological examination of an excised lesion revealed a dense infiltrate of markedly atypical T-lymphoid cells expressing the CD8+ phenotype located in the subcutaneous tissue with histiocyte-phagocytizing apoptotic cells. The ‘bean-bag’ histiocytic cells, the characteristic finding of SPTCL, are considered to be products of haemophagocytosis. In our case the ‘bean-bag’ cells were produced by phagocytosis of apoptotic bodies, as confirmed by electron microscopy. It is suspected that ‘bean-bag’ cells are related not to haemophagocytosis but to phagocytosis of apoptotic cells in the CD8+ T-cell type of SPTCL.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1046/j.1468-3083.2001.00230.x
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