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Digitale Medien

Evidence for serotonin as a possible inhibitory transmitter in some limbic structures (1967)

Eidelberg, E. ; Goldstein, G. P. ; Deza, L.

Springer

Experimental brain research 4 (1967), S. 73-80

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Details

ISSN: 1432-1106

Schlagwort(e): Cats ; Amygdala ; Hippocampus ; Serotonin ; Synapses

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Cats were used for microelectrode recording from single cells in the amygdaloid complex, and for fluorescence histochemical demonstration of monoamines. It was found that the firing rate of amygdaloid neurones decreased sharply following the administration of 5-HTP, the precursor of serotonin. Conversely, it increased after the administration of L-DOPA, the precursor of dopamine and norepinephrine. The fluorescence microscopy studies, after formaldehyde condensation, showed the presence of what appear to be axosomatic synapses containing serotonin on amygdaloid and hippocampal neurones. We conclude that serotonin may be an inhibitory synaptic transmitter in these limbic structures.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00235218

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