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Digitale Medien

Immunohistochemical demonstration of the localization of corticotropin releasing factor-containing neurons in the hypothalamus of mammals including primates (1982)

Kawata, M. ; Hashimoto, K. ; Takahara, J. ; [weitere]

Springer

Anatomy and embryology 165 (1982), S. 303-313

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Details

ISSN: 1432-0568

Schlagwort(e): CRF neurons ; Hypothalamus ; Immunohistochemistry ; PAP ; Mammals

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary The presence of the CRF-containing neurons in the hypothalamus was investigated in four different species (cats, dogs, pigs, and monkeys) by the peroxidase-antiperoxidase technique using specific anti-serum to CRF. In all animals examined, CRF-containing perikarya were found mainly in the paraventricular and supraoptic nuclei, and a small number of the immunoreactive cells were observed in the accessory supraoptic nucleus and the lateral hypothalamic area. The size of the CRF-containing perikarya ranged from 20–35 μm in diameter. These findings suggest that the magnocellular paraventricular and supraoptic nuclei are the center not only of the classical neurosecretory system for the production of the posterior lobe hormones, but also that of the CRF neuronal system.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00305569

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