ISSN:
1471-0528
Quelle:
Blackwell Publishing Journal Backfiles 1879-2005
Thema:
Medizin
Notizen:
Objective To examine how maternal diet in pregnancy and parental body size and birthweight influence an infant's thinness at birth measured by a low ponderal index.Design An observational study of newborn infants and their parents.Setting Southampton, England.Population Five hundred and thirty-eight infants born at term.Main outcome measure Ponderal index at birth.Results Women who had a high intake of carbohydrate in early pregnancy and a low intake of dairy protein in late pregnancy tended to have infants that were thin at birth (P= 0.01 and P= 0.03, respectively, in a simultaneous analysis). Women who themselves had a low birthweight also tended to have thin infants, ponderal index falling from 28.3 kg/m3 to 26.2 kg/m3 as the women's birthweights decreased from more than 4.0 kg to 2.5 kg or less (P 〈 0.0001). Tall fathers had thin infants, but ponderal index was not related to the women's heights or the fathers’ birthweights.Conclusion These associations may reflect constraints on placental development imposed by a woman's nutrition in pregnancy and during her own intrauterine life. Effects of the father's height may be mediated through genetic influences on skeletal growth.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1111/j.1471-0528.1997.tb11975.x
