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  • 1
    Electronic Resource
    Electronic Resource
    Effect of pulse dose cyclophosphamide on the anamnestic immune response in NZB/W mice (1978)
    Springer
    Inflammation research 8 (1978), S. 644-651 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Mice exhibiting a spontaneous SLE-like lethal autoimmunity (female NZB/W hybrids) were given monthy doses of cyclophosphamide (CPA) 240 mg/kg p.o. starting at four months of age. Antibodies to DNA and sheep red blood cells (SRBC) were measured as well as general well being of the mice. The CPA-treated group demonstrated a marked increased in survival compared to the untreated controls with reduction of anti-DNA antibody levels but only a slight inhibition of the anamnestic response to SRBC immunization.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01998895
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