ISSN:
1432-0428
Keywords:
Human proinsulin
;
radioimmunoassay
;
standards
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Two new batches of pancreatic human proinsulin have been compared with biosynthetic human proinsulin. Standards of these three proinsulin preparations were made on the basis of quantitative amino-acid analyses and compared in two proinsulin radioimmunoassays with a proinsulin standard prepared 14 years ago. The curves of the new standards were superimposable. However, they differed considerably from the curve of the old standard which proved to be only one-third of the strength of the new standards, thereby leading to a threefold over-estimation of proinsulin concentrations when the old standard is used. We conclude that the new standards should replace previously used standards.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00304860
