Library

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wurde versucht, mit dem IBM-Zellseparator an gesunden Personen für eine Transfusion ausreichend große Mengen an Granulozyten bei optimalem Reinheitsgrad gegenüber den anderen Blutzellen zu isolieren. Es konnten maximal 1,5×109 Granulozyten bei einem Spender isoliert werden, was etwa dem Gehalt einer Frischblutkonserve entspricht. Der Grund für die geringe Ausbeute wird in der Antikoagulierung des Blutes mit ACD gesehen. Bei Verwendung von Heparin als Antikoagulans ist eine wesentliche Verbesserung der Ausbeute zu erwarten.
    Notes: Summary In summary only that number of granulocytes can be obtained from normal persons as are contained in an amount of 500 ml fresh blood. But contrary to fresh blood, there is only a very small contamination with lymphocytes and thrombocytes. As known from the literature, the amount of 1.5×109 granulocytes is not sufficient to produce a therapeutic effect. On the other hand, the transfusion of donor granulocytes obtained in this way can only be repeated as often as the transfusion of such amount of erythrocytes is allowed. So the isolation of a sufficient amount of granulocytes from normal subjects for transfusion is not possible with the cell separator by this method.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...