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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Medical microbiology and immunology 174 (1985), S. 257-265 
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have investigated the relation between antibiotic resistance and the number of plasmids contained in 44 enterotoxigenic (ETEC) and 69 nonenterotoxigenic (non-ETEC)Escherichia coli strains. Both ETEC and non-ETEC strains were resistant to one or more antibiotics at a similar rate, but multiple resistance in resistant non-ETEC strains was higher than in resistant ETEC strains, showing a significant difference (P〈0.001) when subjected to Student's t test. Among the ETEC strains, those producing both LT and STa enterotoxins were more sensitive to antibiotics than strains producing only a single toxin type. On the other hand, resistant ETEC strains possessed a higher number of plasmids per strain than the resistant non-ETEC strains (P〈0.05 by Student's t test). Consequently, resistance to antibiotics could not be related to the possession of a higher number of plasmids. Furthermore, our results support the hypothesis that there is a generalized incompatibility process between plasmids which code for antibiotic resistance and plasmids which code for enterotoxin production in ETEC strains, at least in those strians producing both LT and STa enterotoxins.
    Type of Medium: Electronic Resource
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