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  • 1
    ISSN: 1432-1076
    Keywords: Group B streptococci: types Ia, Ib, II, III ; IgG antibody levels ; Premature infants ; Early onset septicemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sera from 33 newborn infants with gestational ages ranging from 27 to 41 weeks were tested by radioimmunoassay for IgG antibodies to surface antigens of group B streptococci (GBS) types Ia, Ib, II and III. Antibody levels to GBS antigens were positively correlated to gestational age and birthweight. However, only the correlations for anti-Ia and anti-II antibody levels reached statistical significance. Mean antibody concentrations in infants below 34 weeks of gestation were significantly lower for type Ia (P〈0.001), type II (P〈0.001) and type III (P=0.05) than in infants above this limit. These findings might explain the higher rate of serious GBS-infections found among prematures as compared to full-term infants.
    Type of Medium: Electronic Resource
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