ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
The hydroxyapatite/collagen (HAp/Col) nanocomposite membrane was prepared fromthe HAp/Col nanocomposite fibers. The HAp/Col membrane crosslinked by a vacuum heatingshowed 14±2 (dry) and 1.0±0.1 (wet) MPa in tensile strengths that were enough strength to operatein both cell culture and surgical operations. Histological observation and total DNA amountanalysis demonstrated that human osteoblastic cells, MG63, derived from osteosarcoma on theHAp/Col membrane adhered and proliferated well as the same as those on tissue culture polystyrene(TCPS). Real-time polymerase chain reaction analyses indicated that alkaline phosphatase geneexpression on the HAp/Col membrane was 1.4 times greater than that on TCPS. These resultssuggested that the HAp/Col nanocomposite membrane can be utilized in bone tissue engineeringscaffold as well as bone filler
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/52/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.330-332.313.pdf
