ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
Calcium phosphate ceramics are widely used as bone substitutes since they arebiocompatible and bioactive. Given that their chemical composition is close to natural bone,calcium phosphate ceramics are promising bone substitute materials in orthopaedics, maxillofacialsurgery and dentistry. Hydroxyapatite (HA) and tricalcium phosphate (TCP) are the mostcommonly used calcium phosphates, because their calcium/phosphorus (Ca/P) ratios are close tothat of natural bone and they are relatively stable in physiological environment. Furthermore, othercritical parameters must be accomplished when designing a biomaterial for bone regeneration,namely: pore size, shape and interconnectivity [1]. Porosity is one of the most important factorssince it influences the adhesion, migration nutrient supply and ultimately, proliferation ofmesenchymal stem cells. In this study, HA scaffolds with controlled porosity were obtained andtheir capacity to support human and rat mesenchymal stem cells attachment and proliferation wasevaluated
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/53/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.330-332.1129.pdf
