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  • Articles: DFG German National Licenses  (5)
  • 1980-1984  (4)
  • 1965-1969  (1)
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  • Articles: DFG German National Licenses  (5)
Material
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 16 (1969), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— —An enzyme catalysing the transfer of sulphate from 3′-phosphoadenylsulphate to serotonin was purified from rabbit brain. The purification procedure involved ammonium sulphate fractionation of the 200,000 g supernatant of rabbit brain homogenate, treatment with alumina Cγ, and chromatography on DEAE-cellulose. The enzyme was purified 67-fold from the 200,000 g supernatant of the brain homogenate. The intracranial distribution of the sulphotransferase was investigated and the cerebellum found to have rather high activity. The sulphotransferase activities of rabbit, dog, rat and bovine brains were compared; rabbit brain had the highest activity, followed by dog, rat and bovine brain.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 39 (1980), S. 121-124 
    ISSN: 1432-1106
    Keywords: Amygdala ; Medial preoptic nucleus ; Median eminence ; Rat ; Synaptic plasticity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Stimulation-dependent changes in synaptic effects were observed in medial preoptic nucleus neurones during stimulation of the amygdala or pyriform cortex in anaesthetized female rats. The changes occurred after 35–240 triple pulse stimuli repeated at 0.89 Hz. Median eminence stimulation did not produce any synaptic change. These data show the existence of synaptic plasticity in the neural pathway from the amygdala and pyriform cortex to the medial preoptic nucleus.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 38 (1982), S. 120-122 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The possible mechanism of neuropathic effect of chinoform was investigated using cultured retinal neuroblasts from chick embryos. Retinal neuroblasts completely degenerated by chinoform-ferric chelate within a day. This change, however, was not observed with free chinoform or ferric ion.a-Tocopherol had a potent protective effect on the toxicity of the chelate. From these results, it was concluded that the lipid peroxidation due to ferric ion chelated with chinoform incorporated into the membrane of nerve tissues is the most important step in induction of the neuropathy.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 48 (1982), S. 420-428 
    ISSN: 1432-1106
    Keywords: ADH-neurone ; Amygdala ; Rat ; Supraoptic nucleus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Effects of amygdala stimulation on the discharge activity of antidromically identified supraoptic neurosecretory neurones were studied in male rats anaesthetized with urethane. Stimulation of the medial and the basal amygdala produced excitation or inhibition of discharge activity both in phasically firing (“phasic”) and in continuously firing (”continuous”) neurones. More “phasic” neurones were excited than were inhibited after medial amygdala stimulation. On the other hand, fewer “continuous” neurones were excited by stimulation of the either amygdala area than were inhibited. This difference of responsiveness between “phasic” and “continuous” neurones is statistically significant. Synaptic inputs to supraoptic neurosecretory neurones after amygdala stimulation were also observed in rats with a lesion of the stria terminalis. Supraoptic nucleus stimulation activated antidromically 14 of the 336 amygdala neurones tested. Since “phasic” neurones have been identified as ADH-secreting neurones, it is concluded that ADH-secreting neurones in the rat supraoptic nucleus receive predominantly excitatory synaptic inputs from the medial amygdala and these amygdalar synaptic inputs are mediated by pathways which are at least in part monosynaptic and are not included in the stria terminalis.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 42 (1981), S. 362-370 
    ISSN: 1432-1106
    Keywords: Carotid baroreceptor ; Pain afferents ; Pontine neurone ; Rat ; Supraoptic nucleus neurone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Effects of pressure stimulation of the isolated carotid sinus, of occlusion of the common carotid artery and of tail pinching on the discharge activity of dorsal pontine area neurones and antidromically identified supraoptic neurosecretory neurones were studied in male rats anaesthetized with urethane. Electrical stimulation of the supraoptic nucleus (SON) produced antidromically conducted action potentials in a small number (24/384) of the units recorded in the dorsal pontine area. Pressure pulse stimulation of the isolated carotid sinus inhibited and carotid occlusion facilitated discharge activity in some of the tested dorsal pontine area neurones. In these responsive pontine neurones a transient excitation of grouped discharges was occasionally observed to concur with a small, spontaneous depression of the arterial blood pressure. Tail pinching excited some of these pontine neurones. Histological examination revealed that these responsive neurones were located in the dorsal pontine area close, but ventral and lateral, to the locus coeruleus. Electrical stimulation of the dorsal pons evoked a synaptically mediated excitation in 20 and inhibition in the other seven of the 52 SON units which were identified antidromically after stimulation of the pituitary stalk. Pressure stimulation of the isolated carotid sinus evoked an inhibition of discharge activity in some of the SON units which were excited by dorsal pontine area stimulation. All of the six tested units which showed inhibition after dorsal pontine area stimulation were unresponsive to pressure stimulation. Based on these data, it was concluded that at least some of the neurones which mediate carotid baroreceptor inputs to SON neurosecretory neurones are located in the dorsal pontine area close, but ventral and lateral, to the locus coeruleus and that these dorsal pontine area neurones also mediate converging synaptic inputs originating from somatic pain receptors.
    Type of Medium: Electronic Resource
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