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  • Articles: DFG German National Licenses  (2)
  • Electronic Resource  (2)
  • 2-Brom-2-ethyl-4-butyrolactam  (1)
  • Cat diseases  (1)
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  • Articles: DFG German National Licenses  (2)
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  • Electronic Resource  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Neurological disease and encephalitis in cats experimentally infected with Borna disease virus (1997)
    Springer
    Acta neuropathologica 93 (1997), S. 391-401 
    Details
    ISSN: 1432-0533
    Keywords: Key words Borna disease virus ; Cat diseases ; Encephalomyelitis ; Immunopathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Barrier-bred cats were inoculated intracerebrally with either the rabbit-adapted Borna disease virus (BDV) strain V or a newly isolated feline BDV, obtained from a cat with natural staggering disease (SD). Three out of eight inoculated cats developed neurological signs and non-suppurative encephalitis; all three recovered from the acute stage of disease. Sero-conversion and the development of neutralizing antibodies occurred in all of the virus-inoculated cats. In addition, cats inoculated with feline BDV showed an early peripheral T cell response not present in cats inoculated with BDV strain V, suggesting that the feline virus exerted a more vigorous effect on the immune system. Using immunohistochemistry and a reverse transcriptase-polymerase chain reaction assay, BDV-specific antigen and nucleic acid could be demonstrated in brain samples from each cat with encephalitis, showing that incomplete viral clearance was probably responsible for the maintenance of inflammation. The successful induction of neurological signs and encephalitis in one cat infected with feline BDV, together with the detection of BDV-specific antigen and nucleic acid in the brain, provides strong evidence for the notion that BDV is the etiological agent behind feline SD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010050630
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Über den Nachweis von 2-Brom-2-äthyl-4-hydroxybutyramid und 2-Brom-2-äthyl-4-butyrolactam nach Carbromalgabe (1978)
    Springer
    Archives of toxicology 40 (1978), S. 119-124 
    Details
    ISSN: 1432-0738
    Keywords: Carbromal ; 2-Brom-2-ethylbutyrylcarbamide ; 2-Brom-2-ethyl-4-hydroxybutyramide ; 2-Brom-2-ethyl-4-butyrolactam
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 2-Brom-2-äthyl-4hydroxybutyramid und 2-Brom-2-äthyl-4-butyrolactam sind aus dem Urin von Mäusen, Ratten und Hunden nach Zufuhr von Carbromal oder Bromdiäthylacetamid sowie aus dem Urin carbromalvergifteter Patienten isoliert und mittels Massen-, Kernresonanz- und IR-Spektroskopie identifiziert worden.
    Notes: Abstract 2-Brom-2-ethyl-4-hydroxybutyramide and 2-Brom-2-ethyl-4-butyrolactam have been isolated from the urine of patients with carbromal intoxications as well as from the urine of rat, mouse and dog after the application of either carbromal or bromdiethylacetamide and identified by means of mass-, NMR- and IR spectroscopy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01891966
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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