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  • Articles: DFG German National Licenses  (6)
  • 1985-1989
  • 1975-1979  (3)
  • 1970-1974  (3)
  • 1960-1964
  • 1955-1959
  • 1976  (3)
  • 1972  (3)
Source
  • Articles: DFG German National Licenses  (6)
Material
Years
  • 1985-1989
  • 1975-1979  (3)
  • 1970-1974  (3)
  • 1960-1964
  • 1955-1959
Year
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 3 (1976), S. 0 
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. The effects of glucagon on the secretion of pancreatic juice were investigated using blood-perfused canine pancreas preparations.2. Intravenous administration of glucagon (3–30 μg/kg) to the donor dog elicited a dose-dependent increase in pancreatic secretion. Intra-arterial administration of glucagon (10–100 μg) into the perfused pancreas also elicited increased secretion.3. There were slight increases in amylase concentration of the pancreatic juice with the largest doses of glucagon given by either route.4. Glucagon-induced secretion was not modified by treatment with phentolamine, propranolol, atropine, guanethidine, tetrodotoxin, haloperidol, prostaglandin F2a or calcitonin.5. The results suggest that glucagon acts directly on the exocrine cells of the canine pancreas.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 3 (1976), S. 0 
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Effects of calcitonin on dopamine-, secretin- and pancreozymin-induced pancreatic secretion were investigated in the isolated blood-perfused canine pancreas.2. The volume of pancreatic secretion induced by pancreozymin given intra-arterially (i.a.) was decreased by an i.a. infusion of 1 u/min of calcitonin, but that induced by dopamine or secretin given i.a. was not affected by calcitonin treatment.3. Amylase concentration in pancreatic juice either in spontaneous secretion in the resting state or in that of stimulated secretion by pancreozymin was decreased approximately 30% by calcitonin treatment, but amylase concentration in pancreatic juice induced by dopamine or secretin was not affected by calcitonin treatment.4. Calcitonin had no effect on bicarbonate concentration in pancreatic juice stimulated by these secretagogues.5. Calcium concentration in pancreatic juice in the resting state was reduced about 36% by calcitonin treatment. Calcitonin caused a decrease in a calcium concentration in the pancreozymin-induced secretion, but did not cause any change in the dopamine- or secretin-induced one.6. These results suggest that calcitonin may affect the secretory mechanism of the acinar cells but not that of the ductular cells, and that the acinar cells are active even in the resting state.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Es wurde die Potenz sechs β-adrenergischer Blockierungsmittel auf positiv inotrope Wirkung von Noradrenalin am isolierten, Blut zuführenden Papillarmuskel des Hundes vergleichend untersucht. Die Reihenfolge der Wirksamkeit: Köl366〉pindolol〉C-3〉Y-6124=YB−2 = propranolol (30:10:5:1)
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Mit neu ausgebauter Methode sind 8 ältere und neuere β-Blocker auf ihre Eigenwirkung und ihre Wirksamkeit als Noradrenalin-Antagonisten geprüft worden. Die abgestuften Wirksamkeitszahlen sind: Kö1366 (20)〉Pindolol (10)〉C-3 (5)〉YB-2=Y-6124 (3)〉Propranolol (1)〉Practolol (2/3)〉Sotalol (1/3).
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 29 (1972), S. 189-200 
    ISSN: 1432-1246
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A series of exposure experiments with Triethylaluminum were undertaken using animals, and the following results were obtained: 1. Gas Chromatographic analysis of the exposure gas showed that the gas contained various combustion products of TEA in the air and contained an unidentified substance which had a retention time equivalent to a 6-carbon compound. The substance was assumed to be TEA itself. 2. A moderate systemic effect of “TEA” gas on various organs was observed when it contained considerable amounts of the 6-carbon compound. 3. Characteristic changes in the lungs of animals exposed to “TEA” were found by histological examination. The changes in the lungs were a result of moderate irritation. 4. The effects of exposure to the “TEA-toluene” mixture were more severe in the animals than the effects of “TEA”. Those effects would be mainly due to toluene because the same effects could be seen by the exposure to toluene alone. 5. Direct action of “TEA” on the skin was identical to that of a burn. A possible relation between these results and the clinical symptoms found among some of the workers handling TEA was briefly discussed.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Archives of virology 52 (1976), S. 341-345 
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cordycepin (3′-deoxyadenosine) inhibited viral RNA synthesis in the replication of western equine encephalitis virus, thereby causing a reduction of virus production. The rate of inhibition of viral RNA synthesis was dependent on drug concentration and the period of treatment with the drug. These results suggest that the virus RNA synthesizing system is sensitive to the drug.
    Type of Medium: Electronic Resource
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