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  • Articles: DFG German National Licenses  (6)
  • 1985-1989  (6)
  • 1988  (6)
  • 1
    Electronic Resource
    Electronic Resource
    High-performance liquid chromatographic assay of serum glycated albumin (1988)
    Springer
    Diabetologia 31 (1988), S. 627-631 
    Details
    ISSN: 1432-0428
    Keywords: Affinity chromatography ; anion exchange chromatography ; fructosamine ; haemoglobin A1c ; glycaemic control ; glycated protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A method for determination of serum glycated albumin by high-performance liquid chromatography is presented. The system involves anion exchange chromatography to separate albumin and consecutive boronate affinity chromatography to separate glycated and nonglycated albumin. The method is rapid (20 min), precise (coefficient of variation, 0.7–4.9%), requires only a small sample (5 μl), and can be automated. Assay of glycated albumin by this method is not influenced by the protein concentration of the sample or the presence of glucose. The variation in glycated albumin values in consecutive samples obtained within a day from diabetic patients (coefficient of variation, 2.02±0.65%) was significantly smaller (p〈0.001) than that of values for fructosamine (coefficient of variation, 4.33±2.0%). The values of glycated albumin in normal subjects (20.2±1.6%) were clearly less than those in diabetic patients [39,6±5.4% in 40 Type 1 (insulin-dependent) and 39.4±5.9% in 25 Type 2 (non-insulin-dependent) patients]. The serum glycated albumin level was well correlated with HbA1c in 65 diabetic patients (r=0.60). Because the life span of albumin in the circulation is short, measurement of glycated albumin should be useful as a short-term index of glycaemic control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00264772
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Cervical dislocation of mice induces rapid accumulation of platelet serotonin in the lung (1988)
    Springer
    Inflammation research 25 (1988), S. 48-56 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract As much as 3–8 μg/g wet weight of serotonin (5-hydroxytryptamine, 5HT) has been detected in mouse lung 10 sec after the animal was sacrificed by cervical dislocation. Perfusion of the lung was carried out to determine where the majority of 5HT was located. Of the total 5HT, 84.3% was measured in the perfusate in which 90–98% was recovered in the platelet-rich fraction. When lungs were dissected from mice without cervical dislocation, either after instantaneous killing by irradiation with high power microwaves or under anesthesia, 5HT in the lung was 0.40–1.60 μg/g tissue. These results show that cervical dislocation induces the entrapment of platelets in the pulmonary capillaries within 10 sec. The pulmonary accumulation of 5HT induced by cervical dislocation was approximately 50% inhibited by both prazosin and yohimbine, suggesting that the α-adrenergic receptor plays some part in the process. Norepinephrine but not isoproterenol augmented by 180% the response of pulmonary 5HT to cervical dislocation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01969093
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The second nation-wide survey in Japan of vitamin K deficiency in infancy (1988)
    Springer
    European journal of pediatrics 147 (1988), S. 472-477 
    Details
    ISSN: 1432-1076
    Keywords: Vitamin K deficiency ; Intracranial haemorrhage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Throughout Japan a total of 543 cases of vitamin K deficiency occurring in infants over 2 weeks of age were reported from January 1981 to June 1985. Of these cases, 427 showed no obvious reasons for vitamin K deficiency; this sort of case is known as “idiopathic vitamin K deficiency in infancy”. Another 57 cases had bleeding episodes due to vitamin K deficiency associated with obvious hepatobiliary lesions, chronic diarrhoea, long-term antibiotic therapy, etc; this sort is called “secondary vitamin K deficiency in infacy”. The third group, consisting of 59 cases, was made up of the socalled “near miss” type, in which a haemorrhagic tendency, without any obvious clinical haemorrhage, was discovered by Normotest, at the time of mass screening in most cases. In the idiopathic group, 269 cases (63.0%) developed bleeding episodes between the 1st and 2nd months of age, and 387 cases (90.0%) were entirely breast-fed. Intracranial baemorrhage was observed in 353 cases (82.7%) of this group. Moreover, slight elevation of serum transaminase and direct type bilirubin levels were observed in the idiopathic group. Liver dysfunction of unknown origin may play some role in the onset of vitamin K deficiency in infancy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00441969
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Delayed appearance of blood lactate with reduced frequency breathing during exercise (1988)
    Springer
    European journal of applied physiology 57 (1988), S. 462-466 
    Details
    ISSN: 1439-6327
    Keywords: Reduced frequency breathing ; Hypoventilation ; Lactate removal ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The purpose of the present study was to investigate the blood lactate (LA−) responses to hypoventilation induced by reduced frequency breathing (RFB) during recovery from exercise. Five male subject performed 16 4 min cycling bouts alternating with 16 min rest periods. Exercise intensities were chosen at power outputs corresponding to 30% $$\dot V_{{\text{O}}_{{\text{2 max}}} } $$ at 2mMLA−, $$\dot V_{{\text{O}}_{\text{2}} } $$ at 4 mMLA−, and 90% $$\dot V_{{\text{O}}_{{\text{2 max}}} } $$ in each subject. Breathing frequency was voluntarily controlled starting 10 s before each 3rd min of exercise and maintained throughout the rest of the exercise period. Four different breathing patterns at each exercise intensity were used: normal breathing (NB), breathing every 4 s, breathing every 8 s, and maximal RFB. Except for the NB trials, subjects held their breath at functional residual capacity during each breathing interval. The concentration difference of LA− between the 3rd min sample and the 4th min sample was defined as the lactate change during exercise (Δ LA−ex), and that between the 4th min sample and the sample at the 3rd min after the end of the exercise as the lactate change during recovery (Δ LA−rec). An ANOVA showed significant (p〈0.05) differences in breathing procedures only in ΔLA−rec. ΔLA−rec seemed to increase as compared to NB only at $$\dot V_{{\text{O}}_{\text{2}} } $$ at 4 mMLA− and 90% $$\dot V_{{\text{O}}_{{\text{2 max}}} } $$ , while ΔLA−ex remained unchanged as compared to NB in spite of reduced ∵V A. These results might indicate that RFB inhibited lactate removal from working muscles during exercise.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00417994
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    A dielectric rod waveguide coupled with metal rectangular waveguide (1988)
    Springer
    International journal of infrared and millimeter waves 9 (1988), S. 29-40 
    Details
    ISSN: 1572-9559
    Keywords: dielectric rod waveguide ; near mm wave transmission ; HE11 mode
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Measurements have been done in the millimeter wave region on a composite waveguide which comprises a dielectric rod waveguide connecting two metal rectangular waveguides. Such a waveguide has been used by us in a Josephson harmonic mixer installed in a small metal cryostat, to prevent the thermal invasion from outside environment and to transmit both signal and LO waves with small losses. The measured transmission loss, that is caused mainly by the coupling loss between metal rectangular waveguides (TE10 mode) and a dielectric rod waveguide (HE11 mode), has been less than 2dB in the frequency range of 52–104 GHz.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01010619
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Preparation and radiation-resistance evaluation of glass fibre composites having various epoxy matrices (1988)
    Springer
    Journal of materials science 7 (1988), S. 503-505 
    Details
    ISSN: 1573-4811
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01730706
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    Paper (German National Licenses)
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