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  • Articles: DFG German National Licenses  (7)
  • 1990-1994  (7)
  • 1993  (4)
  • 1992  (3)
Source
  • Articles: DFG German National Licenses  (7)
Material
Years
  • 1990-1994  (7)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 23 (1993), S. 0 
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To determine whether histochemical reactivities of carcinoma-in-situ of the urinary bladder differ from those of invasive transitional cell carcinoma, we tested a profile of eight different lectins and three antibodies directed against blood group-related antigens for 15 cases of carcinoma-in-situ and 26 cases of non-papillary (6 superficially and 20 deeply) invasive transitional cell carcinoma that had been diagnosed according to the histopathological criteria of the International Union against Cancer. For biotin-labelled lectins and monoclonal antibodies to mouse blood group-related antigens, the avidin–biotin peroxidase complex method was applied. Positive histochemical reactions of peanut agglutinin without neuraminidase treatment—PNA N(–)—in the 20 deeply invasive tumour cases were significantly higher than those in the 15 carcinoma-in-situ cases (P〈0.05). In contrast, the reactions of blood group-related antigens in the 20 deeply invasive tumour cases were significantly lower than those in the 15 carcinoma-in-situ cases or the 11 normal controls (P〈0.05). The results confirm previously reported studies of the staining of PNA N(–) and blood group-related antigens on carcinoma-in-situ and invasive tumours of urothelial organs. The application of lectins and blood group-related antigens to the histopathology of urinary bladder cancer may be helpful in the differential diagnosis of carcinoma-in-situ from invasive cancer, but neither PNA N(–) nor blood group-related antigens can be solely reliable in this.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 48 (1992), S. 367-371 
    ISSN: 1420-9071
    Keywords: Tunichrome ; phenylalanine ; ascidian ; tunicates ; blood pigments
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Ascidia ceratodes exposed to14C-phenylalanine in the surrounding seawater incorporates the radiolabel into newly biosynthesized tunichrome molecules. Radioactivity can be detected in tunichrome extracted from circulating blood cells within one day following initial exposure to the radiolabel; weak activity (≤4 μCi/mol tunichrome=22 nmol phenylalanine/mol tunichrome) is detected in 1 to 10 days; significantly higher amounts of radiolabel (57 μCi/mol tunichrome=318 nmol phenylalanine/mol tunichrome) appear 20 days after seawater exposure. Therefore, phenylalanine can function as a precursor in the biosynthesis of tunichrome.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 48 (1992), S. 683-687 
    ISSN: 1420-9071
    Keywords: Suspension cells ; Vigna angularis ; UV irradiation ; endogenous elicitor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Brief irradiation with a germicidal UV lamp of cells of red bean,Vigna angularis, cultured in suspension in a quartz flask caused the release into the culture medium of an endogenous substance with elicitor activity, as well as the accumulation of isoflavone glucoside stress metabolites in the cells. The active compound was fractionated using phenylalanine ammonia lyase (PAL)-inducing activity in fresh cells as a marker. The elicitor active principle appears to be a low molecular weight (〈2000 MW) water-soluble acidic oligosaccharide.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of thermal analysis and calorimetry 38 (1992), S. 1883-1890 
    ISSN: 1572-8943
    Keywords: flow microcalorimeter ; hydrophobic interaction ; molar excess enthalpies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Mittels eines Fluß-Mikrokalorimeters wurden bei 298.15 K im gesamten Konzentrationsintervall die molaren Überschußenthalpien für wäßrige Lösungen aus 3-Methoxy-1-Butanol (3-MB) und 1-Methoxy-2-Butanol (M-2B) gemessen. Anhand der experimentellen Daten erstellten wir den Enthalpiepaar-Wechselwirkungsparameter hxx und erhielten folgende Reihenfolge: hxx(3-MB) ≫ hxx(M-2B) Diese große Abweichung bei hxx legte uns einige neue Faktoren nahe, die einen Einfluß auf die hydrophobe Wechselwirkung haben können: “Grundgerüst”, “Hydroxylgruppen” als auch “Sauerstoffatome”.
    Notes: Abstract Molar excess enthalpies for aqueous solutions of 3-methoxy-1-butanol (3-MB) and 1-methoxy-2-butanol (M-2B) have been measured at 298.15 K over the whole concentration range with a flow microcalorimeter. From the experimental data, we evaluated the enthalpic interaction parameter hxx and obtained the following order:h xx (3 MB)≫ hxx(M-2B) This large difference in hxx. provided us some new factors which might have the influence on hydrophobic interaction: ‘fundamental frame’, ‘hydroxyl group’, and ‘ether oxygen atom’.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 4 (1993), S. 127-131 
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: It has been proposed that a hydrated silica plays an important role in forming a biologically active apatite layer on the surfaces of bioactive glasses and glass-ceramics in the body. Recent experiments have shown that a silica hydrogel actually induces apatite formation on its surface in a simulated body fluid (SBF). In the present study the process of apatite formation on silica gel was investigated by means of thin-film X-ray diffraction, Fourier-transformed infrared reflection spectroscopy and scanning electron microscopic observation of the surface of the silica gel, as well as the measurement of changes in the ion concentration of the fluid. It was found that the induction period for the apatite nucleation on the surface of the silica gel was about 6 days. Once the apatite nuclei were formed they grew, taking a spherulitic form by consuming the calcium and phosphate ions from the surrounding fluid. Each spherulite consisted of a lot of flake that clustered into a petal-like morphology. The flake was carbonate-containing hydroxyapatite of small-crystallites and/or defective structure. The Ca/P ratio of the apatite was estimated as 1.5–1.6. Thus, the apatite formed was able to induce secondary nucleation of the apatite.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 12 (1993), S. 326-328 
    ISSN: 1573-4811
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Hydroxyapatite induction by a synthesized pure silica hydrogel was examined in various simulated body fluids (SBFs) having different magnesium, calcium, and phosphate ion concentrations as well as pH values. The silica hydrogel generated biologically active apatite on its surface by taking up calcium and phosphorous ionic groups from a surrounding SBF that was prepared to emulate the human plasma in inorganic composition. The induction period for apatite nucleation on the surface of the silica was largely decreased with the addition of a small amount of the calcium or phosphate ions to the SBF and with an increase in pH, but increased with the addition of magnesium ion. Bioactivity of bioactive materials like Bioglass® and glass-ceramic A-W was well interpreted in terms of the rate of apatite formation reflected in these results. Moreover, the results provide the basic knowledge for designing new bioactive materials. © 1993 John Wiley & Sons, Inc.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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