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  • Articles: DFG German National Licenses  (8)
  • 2005-2009  (3)
  • 1980-1984  (5)
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  • Articles: DFG German National Licenses  (8)
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  • 1
    Electronic Resource
    Electronic Resource
    Successful steroid pulse treatment in childhood acquired haemophilia with nephrotic syndrome (2005)
    Oxford, UK : Blackwell Science Ltd
    Haemophilia 11 (2005), S. 0 
    Details
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary.  We encountered a 2-year-old boy with acquired haemophilia, which rarely occurs in children, who was complicated with nephrotic syndrome. In mid-August 2001, he was diagnosed to have nephrotic syndrome based on the presence of massive proteinuria and hypoalbuminaemia. Activated partial thromboplastin time (APTT) was normal at 42.4 s at that time. After starting prednisone administration of 2 mg kg−1 day−1, the proteinuria disappeared immediately. However, in early October the same year, subcutaneous ecchymosis and intramuscular bleeding occurred for no apparent reason, and from the examination results his APTT was 106.4 s, factor VIII (FVIII) activity was 〈1%, and the anti-FVIII inhibitor titre was 6.9 BU ml−1. As a result, he was diagnosed to have acquired haemophilia. The anti-nuclear antibody and anti-phospholipid antibody were negative. With recombinant activated FVII, haemostasis was obtained, and after administering three courses of steroid pulse therapy (methyl prednisolone: 20 mg kg−1 day−1 × 3 days), the anti-FVIII inhibitory activity disappeared. An analysis of the immunological and coagulation properties of his FVIII autoantibodies showed the anti-FVIII inhibitory activity to be mediated by IgG1 antibody. In other words, his FVIII inhibitor was a Th1 dominant and it provided a good response to treatment. These findings correlate with those of previous reports. The patient thereafter frequently demonstrated a recurrence of nephrotic syndrome. As a result, he is presently being managed with cyclosporine. However, no recurrence of the anti-FVIII titre has been observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2516.2005.01093.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Loop-mediated isothermal amplification: an emerging technology for detection of fish and shellfish pathogens (2005)
    Oxford, UK : Blackwell Science Ltd
    Journal of fish diseases 28 (2005), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Fish and shellfish diseases are a constant threat to the sustainability and economic viability of aquaculture. Early diagnosis plays a vital role in management of fish and shellfish diseases. Traditionally, various biochemical and serological tests have been used for fish disease diagnosis. However, the time and expertise required for such diagnoses makes it difficult for aquaculturists to easily adopt them under production conditions. Polymerase chain reaction and probe-based nucleic acid detection have become increasingly popular in fish and shellfish diagnostics. Recently, a novel technique called loop-mediated isothermal amplification (LAMP) has been developed, which is highly sensitive and rapid. LAMP has been used for the detection of bacterial, viral, fungal and parasitic diseases in both animal and plants. In aquaculture, LAMP-based detection of pathogens like Edwardsiella tarda, E. ictaluri, Nocardia seriolae, Tetracapsuloides bryosalmonae, white spot syndrome virus and infectious haematopoietic necrosis virus have been reported. In this review, the application of LAMP for the detection of aquaculture-associated pathogens is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.2005.00670.x
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  • 3
    Electronic Resource
    Electronic Resource
    Numerical calculations of elastic scattering amplitudes for high-energy electron scattering by ionized atoms (1980)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 36 (1980), S. 316-321 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The elastic electron scattering factors and phases for eleven alkali and halide ionized atoms, Li+, Li2+, Li3+, Na+, K+, Rb+, Cs+, F-, CI-, Br- and I-, have been calculated by the partial wave method for impact energies of 10, 40, 70 and 100 keV. Clementi analytic Hartree-Fock wavefunctions were used except for Li2+ whose wavefunction was hydrogen-like, Li3+ whose potential was purely Coulombic, and Rb+, Cs+, Br- and I- for which potential functions estimated from the X-ray scattering factors were used. The calculated scattering factors and phases for the ionized atoms have been compared with those for neutral atoms in International Tables for X-ray Crystallography [(1974). Vol. IV, pp. 176-269. Birmingham: Kynoch Press]. It has been found that the difference in the scattering phase between the neutral and ionized atom is almost constant except for small s and that the magnitude of the difference for a given valence of the ionized atom and a particular impact energy is nearly independent of the atomic number.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0567739480000605
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Neuropathological findings of an autopsy case of adult β-galactosidase and neuraminidase deficiency (1983)
    Springer
    Acta neuropathologica 61 (1983), S. 283-290 
    Details
    ISSN: 1432-0533
    Keywords: β-Galactosidase and neuraminidase deficiency ; Neuronal inclusion bodies ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An autopsy case of a Japanese male with familial β-galactosidase and neuraminidase deficiency is reported. The clinical picture was characterized by adult onset, a gargoyle-like face, cerebellar ataxia, myoclonus, convulsions, retinal degeneration and cortical blindness. Histopathologically, most neurons seemed to have become degenerated in the whole cerebral cortex. Moreover, the calcarine cortex appeared spongy with depopulation of nerve cells. Stuffed neurons or neuronal storage changes were found throughout the brain, especially in the motor nuclei of the spinal cord and brain stem. The inclusions in the stuffed neurons revealed various profiles on the electron microscope. They were composed of membranous lamellar and/or multilamellar structures, often accompanying vacuoles and reminiscent of lipofuscin-like profiles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691999
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Micro-Columnar Crystals with (-O=V-Pd-)〈sub〉n〈/sub〉 Infinite Chain Structures Assembled by Hetero-Dinuclear Metal Complexes (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Advanced materials research Vol. 11-12 (Feb. 2006), p. 273-276 
    Details
    ISSN: 1662-8985
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The inorganic and organic hybrid compound, [O=VPd(2-Pyd-)4]n (2-Pyd- = 2-pyridonate)(1), was synthesized by assembling its monomer units in the organic solution. X-ray absorptionspectroscopic (XAFS) studies indicated that oxidation states of the vanadium and palladium ions in 1were +IV and +II, and the distance between them was estimated to be 2.698-2.700 Å. Scanningelectron microscope (SEM) observation revealed that the compound 1 shapes in long columnarcrystals with micrometer-sized cross section. EXAFS and IR studies suggested that the O=V oxygenatom interacted to the central palladium ion in the neighboring monomer unit, forming the inorganicinfinite chain structure, -(O=V-Pd)n-, in the columnar crystals of 1
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/39/transtech_doi~10.4028%252Fwww.scientific.net%252FAMR.11-12.273.pdf
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  • 6
    Electronic Resource
    Electronic Resource
    Energy-dependent lysosomal wrapping mechanism (LWM) during autophagolysosome formation (1982)
    Springer
    Histochemistry and cell biology 76 (1982), S. 479-488 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The relation of lysosomes to autophagy, in particular the lysosomal wrapping mechanism (LWM) is investigated ultracytochemically from the viewpoint of demonstrations of energy dependency of the LWM. An induction of the LWM was made in mouse subcutaneous histiocytes by subcutaneous administration of ovalbumin. Prior administration of the inhibitor of glycolysis (2-deoxyglucose) alone and of the oxidative phospholylation (sodium azide or 2,4-dinitrophenol) alone did not prevent the occurence of the LWM following ovalbumin administration, but a prior administration of a mixture of 2-deoxyglucose and 2,4-dinitrophenol or 2-deoxyglucose and sodium azide prevented the occurence of the LWM. These results suggest that in order for the LWM to take place ATP is required as an energy source.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00489903
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Intracellular activity and morphology of the prefrontal neurons related to visual attention task in behaving monkeys (1981)
    Springer
    Experimental brain research 41 (1981), S. 195-198 
    Details
    ISSN: 1432-1106
    Keywords: Intracellular recording ; Monkey prefrontal cortex ; Attention neuron ; HRP ; Morphology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neurons of the prefrontal-premotor cortex, which had been studied electorophysiologically during a modified reaction time task, were identified by intracellular pressure micro-injection of horseradish peroxidase (HRP). The cells were classified into those showing a sustained vs. transient change in activity during performance of the task. Cells showing a sustained response were found to have their somata in layers III and VI and cells showing transient responses were found to have their somata in layers II and III. All cells were pyramidal cells with spiny dendrites.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236610
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Debye-Waller parameter of palladium metal powders (1983)
    Springer
    Journal of materials science 18 (1983), S. 1803-1809 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The Debye—Waller parameters were determined at room temperature and around 90 K for palladium metal powders with different particle sizes. The effective values obtained were divided into the dynamic component B d, which is due to the thermal vibration of the constituent atoms and are temperature dependent, and the static component B s, which is probably due to the static displacement of the atoms and is temperature independent. The Debye temperature θ D calculated from the component B d decreased with the increase in the component B s, of which the relation was able to extrapolate to the θd-value determined on single crystals at B s = 0. The decrease in θ D was qualitatively explained by using a simple core-shell model, the shell part having as low a θ D-value as 140 K.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00542077
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