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  • Articles: DFG German National Licenses  (4)
  • 1995-1999
  • 1990-1994  (4)
  • Polymeremulsion  (3)
  • BCNU  (1)
Source
  • Articles: DFG German National Licenses  (4)
Material
Years
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of 11C-labelled BCNU and SarCNU in gliomas studied by PET (1991)
    Springer
    Journal of neuro-oncology 10 (1991), S. 47-55 
    Details
    ISSN: 1573-7373
    Keywords: nitrosoureas ; glioma ; BCNU ; SarCNU ; PET ; chemotherapy ; brain tumor ; BBB
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This paper describes the study of the pharmacodynamics of two 11C-labelled nitrosoureas, 1,3-bis-(2-chloroethyl) nitrosourea (BNCU) and sarcosinamide chloroethylnitrosourea (SarCNU), both labelled in the carbonyl position. Distribution of the radioactivity as measured by positron emission tomography was compared to the distribution of radioactivity observed after injection of 68Ga-EDTA, this being used as an indicator of the blood-brain barrier integrity around the brain tumor. Data suggest that the new nitrosourea, SarCNU, most likely enters brain tissue by different mechanism(s) than BCNU, which enters by diffusion. Data also indicate that use of SarCNU may result in a better tumor to brain ratio than BCNU.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00151246
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Estimation of distribution of vinyl groups in micron-sized monodisperse polymer microspheres by bromine titration method (1991)
    Springer
    Colloid & polymer science 269 (1991), S. 1126-1132 
    Details
    ISSN: 1435-1536
    Keywords: Polymeremulsion ; microsphere ; vinylgroup ; brominetitration ; dispersionpolymerization ; seededpolymerization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The distribution of vinyl groups in polystyrene/poly(styrene-divinylbenzene) (PS/P(S-DVB)) composite microspheres produced by seeded copolymerization of S and DVB in the presence of 2.1-μm monodisperse PS seed particles was estimated from the amount detected with bromine titration method as a function of the reaction time under various conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00654120
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Preferential adsorption of bovine serum albumin dimer onto polymer microspheres having a heterogeneous surface consisting of hydrophobic and hydrophilic parts (1990)
    Springer
    Colloid & polymer science 268 (1990), S. 598-603 
    Details
    ISSN: 1435-1536
    Keywords: Polymeremulsion ; polymermicrosphhere ; bovineserumalbumin ; proteinadsurption ; surfacehydrophilicity ; surfaceheterogeneity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The adsorption behaviors of bovine serum albumin (BSA) containing both dimeric and monomeric species onto polymer microspheres were examined using various homopolymers and poly(2-hydroxyethyl methacrylate)/polystyrene composite microspheres which were produced by the emulsifier-free (seeded) emulsion polymerization technique. The preferential adsorption of the BSA dimer was clearly observed in an optimum region of the surface hydrophilicities of the polymer microspheres. The preferential adsorption of the BSA dimer onto the composite polymer microspheres having heterogeneous surfaces consisting of hydrophilic and hydrophobic parts was more marked than those onto the homopolymer and copolymer microspheres having homogeneous surfaces.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01410399
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Preparation of micron-size monodisperse polymer microspheres having cationic groups (1992)
    Springer
    Colloid & polymer science 270 (1992), S. 733-737 
    Details
    ISSN: 1435-1536
    Keywords: Polymeremulsion ; microsphere ; chloromethylgroup ; polyamine ; cationicgroup ; dispersionpolymerization ; seededpolymerization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Micron-size monodisperse crosslinked polymer microspheres having chloromethyl groups were prepared by seeded copolymerization of styrene, divinylbenzene, and chloromethylstyrene in the presence of 2.1-μ monodisperse polystyrene seed particles produced by dispersion polymerization. The modification reaction of chloromethyl groups on the surfaces with polyamines such as triethylenetetramine and ethylenediamine was carried out. From the measurements of ξ potential and the amount of chloride ion released, the introduction of a large number of cationic groups at the surfaces was confirmed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00776143
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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