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  • Articles: DFG German National Licenses  (1)
  • 1970-1974  (1)
  • 1940-1944
  • Acid secretion  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 50 (1972), S. 744-750 
    ISSN: 1432-1440
    Keywords: Acid secretion ; Parietal cells ; Chronic-atrophic gastritis ; Duodenal ulcer ; Säuresekretion ; Parietalzellen ; chronischatrophische Gastritis ; Ulcus duodeni
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei männlichen Kontrollpersonen, Patienten mit Ulcus duodeni und mit chronisch-atrophischer Gastritis wurde aus Biopsiematerial der Korpusschleimhaut die Parietalzellzahl pro Areal Schleimhautoberfläche mit Hilfe einer histochemischen Reaktion und die maximale Säuresekretion mit Hilfe des Pentagastrininfusionstestes bestimmt. Bei den Patienten mit Ulcus duodeni fand sich eine signifikante Zunahme und bei den Patienten mit chronisch-atrophischer Gastritis eine signifikante Abnahme der bestimmten Parameter. Zwischen der Parietalzelldichte in Biopsiematerial und maximaler Säuresekretion bestand eine deutliche lineare Korrelation, die sich allerdings auch als polynominale Regression 2. Grades ausdrücken ließ.
    Notes: Summary Male patients with duodenal ulcer, chronicatrophic gastritis, and controls without gastrointestinal diseases were examined with respect to the relationship of their maximal acid output and parietal cell mass in gastric mucosal biopsies. Maximal acid output was measured using the pentagastrin infusion test. Parietal cells were marked histochemically in fresh frozen sections by means of their SDH-activity. The following results were obtained: 1. Maximal acid output (MAO) and parietal cell mass were significantly increased in the duodenal ulcer group, while these values were significantly decreased in the patients with chronic-atrophic gastritis. 2. Parietal cell density in biopsy material was closely related to the MAO irrespective of the group investigated. 3. This relationship was calculated as a linear one and could be further improved when expressed as a binominal regression.
    Type of Medium: Electronic Resource
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