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  • Articles: DFG German National Licenses  (4)
  • Alcohol dehydrogenase  (2)
  • (2-Pyrrolidinylmethoxo)borane, anomalous dimer  (1)
  • 22E65  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Overexpression of ADH1 confers hyper-resistance to formaldehyde in Saccharomyces cerevisiae (1996)
    Springer
    Current genetics 29 (1996), S. 437-440 
    Details
    ISSN: 1432-0983
    Keywords: Key words Yeast ; Formaldehyde ; Hyper-resistance ; Alcohol dehydrogenase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  In an attempt to clone genes involved in resistance to formaldehyde we have screened a genomic library based on the episomal plasmid YEp24 for the ability to increase resistance to formaldehyde in a wild-type strain. In addition to SFA, the gene encoding the formaldehyde dehydrogenase Adh5, an enzyme most potent in formaldehyde de-toxification, we isolated a second plasmid that conferred a less pronounced but significant hyper-resistance to formaldehyde. Its passenger DNA contained the gene ADH1, encoding alcohol dehydrogenase 1 (EC 1.1.1.1), which could be shown to be responsible for the observed hyper-resistance phenotype. Construction of an adh1-0 mutant revealed that yeast lacking a functional ADH1 gene is sensitive to formaldehyde. While glutathione is essential for Adh5-mediated formaldehyde de-toxification, Adh1 reduced formaldehyde best in the absence of this thiol compound. Evidence is presented that formaldehyde is a substrate for Adh1 in vivo and in vitro and that its cellular de-toxification employs a reductive step that may yield methanol.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002940050068
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Overexpression ofADH1 confers hyper-resistance to formaldehyde inSaccharomyces cerevisiae (1996)
    Springer
    Current genetics 29 (1996), S. 437-440 
    Details
    ISSN: 1432-0983
    Keywords: Yeast ; Formaldehyde ; Hyper-resistance ; Alcohol dehydrogenase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract In an attempt to clone genes involved in resistance to formaldehyde we have screened a genomic library based on the episomal plasmid YEp24 for the ability to increase resistance to formaldehyde in a wild-type strain. In addition toSFA, the gene encoding the formaldehyde dehydrogenase Adh5, an enzyme most potent in formaldehyde de-toxification, we isolated a second plasmid that conferred a less pronounced but significant hyper-resistance to formaldehyde. Its passenger DNA contained the geneADH1, encoding alcohol dehydrogenase 1 (EC 1.1.1.1), which could be shown to be responsible for the observed hyper-resistance phenotype. Construction of anadh1-0 mutant revealed that yeast lacking a functionalADH1 gene is sensitive to formaldehyde. While glutathione is essential for Adh5-mediated formaldehyde de-toxification, Adh1 reduced formaldehyde best in the absence of this thiol compound. Evidence is presented that formaldehyde is a substrate for Adh1 in vivo and in vitro and that its cellular de-toxification employs a reductive step that may yield methanol.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02221511
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Lowest weight representations of some infinite dimensional groups on fock spaces (1990)
    Springer
    Acta applicandae mathematicae 18 (1990), S. 59-84 
    Details
    ISSN: 1572-9036
    Keywords: 22E65 ; 22E70 ; Highest weight modules ; CCR algebras ; representation theory
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract The results of Kashiwara and Vergne on the decomposition of the tensor products of the ‘Segal-Shale-Weil representation’ are extended to the infinite dimensional case and give all unitary lowest weight representations. Our methods are basically algebraic. When restricted to the finite dimensional case, they yield a new proof.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00822205
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Contribution to the Chemistry of Boron, 235. Reactions of Prolinol with Borane-Tetrahydrofuran: Anomalous Dimerization of a 1,3,2-Oxazaborolidine (1997)
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 130 (1997), S. 241-246 
    Details
    ISSN: 0009-2940
    Keywords: (2-Pyrrolidinylmethoxo)borane, anomalous dimer ; 5-Phenyl-3,4-dimethyl-1,3,2-oxazaborolidine, anomalous dimer ; Reaction intermediates ; Boron compounds ; Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The reaction of (S)-prolinol (LH) with H3B · THF proceeds via [L2BH2〈]BH4, which decomposes with elimination of hydrogen at ca. -40°C to give the BH3 adduct of spirocyclic 7. On heating, 7 loses more H2 to give the “anomalous” dimerization product 11, which features a tetracoordinated B atom in a “tetrahedral” BN2O2 unit and another B atom in an N2BH2 environment. It is also shown that the product resulting from the reaction of pseudoephedrin with H3B·THF undergoes an analogous anomalous dimerization, affording product 8.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cber.19971300217
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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