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  • Articles: DFG German National Licenses  (3)
  • Epidemiology  (2)
  • (Ketone bodies)  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Hyperammonemia decreases body fat content in rat
    Amsterdam : Elsevier
    FEBS Letters 249 (1989), S. 261-263 
    Details
    ISSN: 0014-5793
    Keywords: (Ketone bodies) ; Acetyl-CoA ; Body composition ; Carnitine ; Hyperammonemia ; Lipid metabolism
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(89)80636-2
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Body size, estrogen use and thiazide diuretic use affect 5-year radial bone loss in postmenopausal women (1993)
    Springer
    Osteoporosis international 3 (1993), S. 314-321 
    Details
    ISSN: 1433-2965
    Keywords: Bone ; Bone loss ; Epidemiology ; Estrogen ; Prospective study ; Thiazide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Understanding factors associated with more rapid bone mineral loss among aging women is important for establishing preventive strategies for intervention. This study reports factors associated with the 5-year change in radial bone mineral density (BMD) determined prospectively in 435 women aged 55–80 years at baseline. The baseline study included measurement of radial BMD (gm/cm2) by single photon densitometry and personal interview. The baseline protocol was replicated 5 years later in a follow-up study. Women with a lower baseline weight or Quetelet index, smaller triceps skinfold and less arm muscle area had significantly greater 5-year bone loss (p=0.001). Current users of estrogens had less radial bone loss (2.8% vs 7.3%,p=0.0005) than women not currently using estrogens. Current users of estrogen had significantly less 5-year loss if use had been for 5 years or longer (−1.0% vs −6.9%,p=0.05). Current users of the thiazide class of medications had less 5-year radial bone loss (5.0% vs 7.4%,p=0.0035) than women without current thiazide use. Baseline dietary calcium, alcohol consumption and smoking were not associated with BMD change. This suggests that greater body size, and current use of estrogens or thiazide antihypertensives are associated with less radial bone mass loss in a 5-year period among postmenopausal women.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01637317
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Drug data coding and analysis in epidemiologic studies (1994)
    Springer
    European journal of epidemiology 10 (1994), S. 405-411 
    Details
    ISSN: 1573-7284
    Keywords: Classification ; Clinical pharmacology ; Data bases ; Drugs ; Epidemiology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In epidemiologic studies that collect comprehensive information on medication use, the complexity of dealing with a large number of trade and generic names may limit the utilization of these data bases. This paper shows the specific advantage of using two coding systems, one to maximize efficiency of data entry, and the other to facilitate analysis by organizing the drug ingredients into hierarchical categories. The approach used by two large surveys, one in the USA and one in Italy, is described: the Established Populations for Epidemiologic Studies of the Elderly (EPESE) and the ‘Gruppo Italiano di Farmacovigilanza nell' Anziano’ (GIFA). To enter the medications into a computerized database, codes matching the drug product names are needed. In the EPESE the prescription and over the counter drug products are coded with the Drug Products Information Coding System (DPICS) and the Iowa Nonprescription Drug Products Information Coding System (INDPICS), respectively. The GIFA study uses the coding system of the Italian Ministry of Health (MINSAN), with a unique numeric code for each drug product available in Italy. To simplify the analytical process the drug entry codes are converted into hierarchical coding systems with unique codes for specific drug ingredients, chemical and therapeutic categories. The EPESE and GIFA drug data are coded with the Iowa Drug Information System (IDIS) ingredient codes, and the Anatomical Therapeutic and chemical (ATC) codes, respectively. Examples are provided that show coding of diuretics in these two studies and demonstrate the analytic advantages of these systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01719664
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    Paper (German National Licenses)
    Fulltext
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