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  • Articles: DFG German National Licenses  (5)
  • Telomere  (2)
  • evolutionary algorithms  (2)
  • 25.70.Lm  (1)
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  • Articles: DFG German National Licenses  (5)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of intelligent manufacturing 9 (1998), S. 289-294 
    ISSN: 1572-8145
    Keywords: Manufacturing process chain ; modelling ; optimization ; neural networks ; evolutionary algorithms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Today's manufacturing methods are caught between the growing need for quality, high process safety, minimal manufacturing costs, and short manufacturing times. In order to meet these demands, process setting parameters have to be chosen in the best possible way, according to demand on quality. For such optimization it is necessary to represent the processes in a model. Due to the enormous complexity of many processes and the high number of influencing parameters, however, conventional approaches to modelling and optimization are no longer sufficient. In this article it is shown how, by means of applying neural networks for process modelling, even these highly complex interdependencies can be learned. That way both process and quality parameters can be assessed before or during processing. By connecting them with corresponding cost models, it is possible to optimize processes with the help of evolutionary algorithms. Using examples of different manufacturing processes, the possi bilities for process modelling and optimization with neural networks and evolutionary algorithms are demonstrated.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of intelligent manufacturing 9 (1998), S. 331-338 
    ISSN: 1572-8145
    Keywords: Simulation ; modelling ; machine learning ; evolutionary algorithms ; artificial neural network
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The use of simulation technology as a tool for planning and control is of increasing significance in most fields of production. The main part of the expenditure concerning simulation analyses is the modelling of the considered production. Despite the use of modern building-block-oriented modelling technology, this modelling can often not be done by the user, but only by external experts. Against this backdrop, an adaptive simulation system is being developed by the Institute for Industrial Manufacturing and Management (IFF) at the University of Stuttgart. It independently adapts to real production processes, i.e. it learns about the interdependencies of production processes, and, in this way, supports the user in constructing and maintaining the model. In terms of information technology, the research in the field of artificial intelligence, especially in the subdomain of machine learning, is the basis for the realization of such adaptive systems.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 101 (2000), S. 7-14 
    ISSN: 1432-2242
    Keywords: Key words Pinus ; Gymnosperms ; Simple sequence repeats ; Microsatellites ; Minisatellites ; Telomere
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  The abundance and genomic organization of six simple sequence repeats, consisting of di-, tri-, and tetranucleotide sequence motifs, and a minisatellite repeat have been analyzed in different gymnosperms by Southern hybridization. Within the gymnosperm genomes investigated, the abundance and genomic organization of micro- and minisatellite repeats largely follows taxonomic groupings. We found that only particular simple sequence repeat motifs are amplified in gymnosperm genomes, while others such as (CAC)5 and (GACA)4 are present in only low copy numbers. The variation in abundance of simple sequence motifs reflects a similar situation to that found in angiosperms. Species of the two- and three-needle pine section Pinus are relatively conserved and can be distinguished from Pinus strobus which belongs to the five-needle pine section Strobus. The hybridization pattern of Picea species, bald cypress and gingko were different from the patterns detected in the Pinus species. Furthermore, sequences with homology to the plant telomeric repeat (TTTAGGG)n have been analyzed in the same set of gymnosperms. Telomere-like repeats are highly amplified within two- and three- needle pine genomes, such as slash pine (Pinus elliottii Engelm. var. elliottii), compared to P. strobus, Picea species, bald cypress and gingko. P. elliottii var. elliottii was used as a representative species to investigate the chromosomal organization of telomere-like sequences by fluorescence in situ hybridization (FISH). The telomere-like sequences are not restricted to the ends of chromosomes; they form large intercalary and pericentric blocks showing that they are a repeated component of the slash pine genome.Conifers have genomes larger than 20000 Mbp, and our results clearly demonstrate that repeats of low sequence complexity, such to (CA)8, (GA)8, (GGAT)4 and (GATA)4, and minisatellite- and telomere-like sequences represent a large fraction of the repetitive DNA of these species. The striking differences in abundance and genome organization of the various repeat motifs suggest that these repetitive sequences evolved differently in the gymnosperm genomes investigated.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2242
    Keywords: rDNA sites ; Centromeric repetitive DNA ; Telomere ; In situ hybridization ; Southern hybridization ; Ag-NOR ; Cowpea ; Physical maps
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A knowledge of genome organization is important for understanding how genomes function and evolve, and provide information likely to be useful in plant breeding programmes involving hybridization and genetic manipulation. Molecular techniques, including in situ hybridization, molecular cloning and DNA sequencing, are proving valuable tools to investigate the structure, organization, and diversity of chromosomes in agricultural crops. Heterologous labelled 18 s-5.8 s-25 s (pTa71) and 5 s rDNAs (pTa794) were used for in situ hybridization on Vigna unguiculata (L.) Walp. chromosomes. Hybridization with 18 s-5.8 s-25 s rRNA gene probes occurred at the same chromosomal sites which were positive to the CMA fluorochrome. Silver staining of nucleolar-organizing regions indicated that all the rDNA sites detected using the 18 s-5.8 s-25 s rRNA gene probe possessed active genes. Degenerate telomeric repeats gave hybridization signals at the telomeres of most chromosomes and no intercalary sites were detected at metaphase; the sequences appear to have no preferential distribution in interphase nuclei. A repetitive DraI family from V. unguiculata was cloned (pVuKB1) and characterized. The DraI repeat is 488 nucleotides long, AT rich (74%), and hybridized on all chromosomes in the centromeric areas. The presence of this sequence family was investigated by Southern hybridization in different Vigna species and other Leguminoseae. It was only detected in V. unguiculata, and hence represents a species-specific DNA sequence.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1434-601X
    Keywords: 25.70.Lm ; Mn
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Correlations between two intermediate-mass fragments resulting from 840 MeV32S projectiles interacting with197Au were measured. The angular correlations and absolute two-fragment cross sections agree with predictions of a semi-microscopic model for direct dynamic projectile break-up. This suggests a predominantly direct mechanism for the production of intermediate-mass fragment pairs. It is argued that the intensity of such a channel which, compared to decays yieldingα particles, is much larger than observed for the sequential decay of corresponding primary excited nuclei, supports the direct-break-up interpretation. The model mechanism yields also strongly damped projectile fragments of intermediate mass.
    Type of Medium: Electronic Resource
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