Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Articles: DFG German National Licenses  (4)
  • 6-Hydroxydopamine  (2)
  • Alouatta  (1)
  • Arthroscopic measurement  (1)
Source
  • Articles: DFG German National Licenses  (4)
Material
Years
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    In vivo monitoring of circulation in the intact anterior cruciate ligament using the laser Doppler flowmeter (1993)
    Springer
    Knee surgery, sports traumatology, arthroscopy 1 (1993), S. 76-79 
    Details
    ISSN: 1433-7347
    Keywords: Laser flowmetry ; Arthroscopic measurement ; Microcirculation ; Blood cell flux ; Laser-Flowmetrie ; Mikrozirkulation ; Arthroskopische Messung ; Vorderes Kreuzband
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Sports Science
    Description / Table of Contents: Zusammenfassung Die Laser-Doppler-Flowmetrie gestattet den Nachweis der Durchblutung im mikrokapillären Bereich von Strukturen unter in vivo-Bedingungen. Wir verwendeten das Lasergerät der Firma Perimed (Schweden) und eine Spezialsonde um die kapilläre Durchblutung des vorderen Kreuzbandes während eines arthroskopischen Eingriffs nachzuweisen. Dabei erhält man Meßwerte in Millivolt, welche relativer Natur sind, ein absoluter Wert der Kapillardurchblutung in Volumen pro Zeiteinheit kann dadurch nich bestimmt werden. Unter standardisierten Bedingungen erfolgte bei 11 Patienten die Durchblutungsmessung und simultane Aufzeichnung auf einem 2-Kanal-Schreiber. In allen Fällen konnten herzsynchrone Pulsationen der kapillären Durchblutung des vorderen Kreuzbandes an 3 Meßpunkten nachgewiesen werden, welche bei Schließen der Blutsperre zur Gänze verschwanden. Wir fanden eine große individuelle Schwankungsbreite der sogenannten Blood-Cell-Flux-Werte von 30 mV bis 620 mV. Die Höhe der herzsynchronen Pulsationen schwankte zwischen 20 mV und 240 mV. Zwischen den einzelnen Meßpunkten oder zwischen den Fluxwerten und der Höhe der Pulsationen konnte nur ein vager Zusammenhang in der linearen Regressionsanalyse gefunden werden, kein Zusammenhang war zwischen den Fluxwerten und dem Blutdruck bzw. dem roten Blutbild nachzuweisen.
    Notes: Abstract Laser Doppler flowmetry permits observation of circulation in the microcapillary regions of structures under in vivo conditions. We used a laser device manufactured by the Swedish company Perimed and a special probe to observe the capillary circulation in the anterior cruciate ligament during arthroscopic surgery. This produces measured values in millivolts: these values are relative in nature and cannot be used to determine an absolute value for capillary circulation by volume per unit time. Under standardized conditions, circulation measurements and simultaneous recordings with a twochannel recorder were made from 11 patients. In all cases, pulsations of the capillary circulation synchronous with the heart beat could be seen on three measuring points on the anterior cruciate ligament; these disappeared upon complete deprivation of blood supply. We found a large individual range of variation in the so-called blood cell flux values from 30 to 620mV. The magnitude of the heart-synchronous pulsations ranged between 20 and 240 mV. Only vague linear relationships were found (a) between the individual measuring points and (b) between the flux values and the magnitude of pulsation; there was no relationship between the flux values and blood pressure and/or red blood count (erythrocyte count, hemoglobin, hematocrit).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01565456
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Effects of systemic administration of 6-hydroxydopamine on the circumventricular organs in nonhuman primates (1978)
    Springer
    Cell & tissue research 187 (1978), S. 115-127 
    Details
    ISSN: 1432-0878
    Keywords: Area postrema ; 6-Hydroxydopamine ; Degenerative changes ; Ultrastructure ; Cynomolgus and squirrel monkeys
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary 6-Hydroxydopamine (6-OH-DA) has been shown to produce degenerative changes in noradrenergic nerve terminals and preterminals in the CNS following intracisternal, intraventricular or direct injection into the brain parenchyma. Systemic injection of 6-OH-DA is known to result in degenerative changes in noradrenergic terminals in the peripheral nervous system. However, only a few studies have been carried out on the effects of systemic injections of 6 OH-DA on noradrenergic terminals in the CNS. In the present study cynomolgus and squirrel monkeys were injected intravenously on two successive days with total doses of 350mg/kg and 150 mg/kg of 6-OH-DA, respectively, and sacrificed at 2 and 24 h following the second injection. Degenerative changes in the area postrema (AP) neurons in all injected animals were characterized by a generalized increase in electron density of cytoplasmic elements in axonal terminals and preterminals. Multilamellar bodies, clusters of clear and dense core vesicles, increased numbers of secondary lysosomes, and an increase in the number of glycogen granules were observed in these structures. In astrocytes the amount of glycogen increased markedly in injected animals, but no other glial alterations were observed. The number of mast cells in the AP was greater in injected than in noninjected animals, both in the perivascular spaces (PVS) and in parenchymal locations. Cell processes in the PVS were occasionally observed to contain electron dense bodies, and degenerative changes were seen in supraependymal processes in some injected animals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00220623
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Effects of systemic administration of 6-hydroxydopamine on the circumventricular organs in nonhuman primates (1978)
    Springer
    Cell & tissue research 191 (1978), S. 141-150 
    Details
    ISSN: 1432-0878
    Keywords: Subfornical organ ; Third ventricle ; 6-Hydroxydopamine ; Electron microscopy ; Primate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The neurotoxin 6-hydroxydopamine (6-OH-DA) has been shown to produces degenerative changes in noradrenergic nerve terminals and preterminals in the CNS following intracisternal, intraventricular, and stereotaxic injection into the brain parenchyma. Systemic injections of this drug are also known to result in degenerative changes in noradrenergic terminals in the peripheral nervous system and in the circumventricular organs (CVO; areas of the CNS which lie outside the blood brain barrier). In the present study eight adult female cynomolgus monkeys were employed. The four experimental animals were injected on two successive days with 150 and 200 mg/kg 6-OH-DA, respectively. The four controls received only the diluent consisting of 0.1% ascorbic acid in normal saline. Two animals from each of the experimental and control groups were sacrificed at 2 h and 24 h after the second injection. Degenerative changes in the SFO neurons were characterized by a generalized increase in electron density of cytoplasmic elements in axonal terminals and preterminals. Multilamellar bodies, and increases in the number of dense core vesicles, dense bodies and secondary lysosomes were also observed after treatment with 6-OH-DA. The neurons showed clumping of mitochondria, which also appeared to be undergoing degenerative changes. The vacuoles in some supraependymal cells were greatly dilated as was the Golgi apparatus in the ependymal cells. The ependymal cell layer appeared to be intact, but there were areas immediately deep to this cell layer that contained large extracellular spaces. This increase in extracellular space was also commonly observed surrounding the perivascular spaces. These phenomena greatly contribute to the “spongy” appearance that the SFO takes on after 6-OH-DA administration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00223222
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Taste areas of the plica sublingualis of Alouatta and Aotus (Primates, Platyrrhini) (1977)
    Springer
    Cell & tissue research 177 (1977), S. 415-429 
    Details
    ISSN: 1432-0878
    Keywords: Plica sublingualis ; Taste area ; Aotus ; Alouatta ; Platyrrhini, primates
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A conspicuous accumulation of taste buds occurs in the rostral part of the plica sublingualis (“frenal lamella”) of Alouatta and Aotus forming taste areas (area gustatoria) superficially situated in the oral mucous membrane. They are found in close vicinity to the orifices of the sublingual salivary glands, but are lacking in the aboral part of the plica sublingualis. They do not occur in all primate species studied. A taste area does not projects above the surface of the surrounding tissue like a papilla. The taste buds open not in crypts or furrows of the oral mucosa, but directly into the spatium sublinguale of the oral cavity proper. In the anterior part of the cavum oris proprium different kinds and very differentiated qualities of sensorial information are perceived (touch, taste, olfaction, temperature). It is conceivable that the taste areas play an important role in perceiving fresh saliva, together with the other sensorial structures in this part of the mouth. This problem can be solved experimentally and by behavioral studies. In addition to its topographical relation to the tongue, the organon sublinguale of Callicebus is structurally very similar to the plica sublingualis of Aotus and Alouatta. Since a sublingua does not occur in New World monkeys, it can be concluded that this organ represents a plica sublingualis which became adherent to the undersurface of the tongue. This study was carried out at the Delta Regional Primate Research Center, Covington, Louisiana, U.S.A., and the Department of Zoology and Comparative Anatomy of the University of Kassel, Germany. The study was supported by NIH Grant No. 5-RO1-DEO 3665-02 DEN and by a “U.S. Senior Scientist Award” from the Humboldt Foundation (Bonn, Germany)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00220315
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...