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  • Articles: DFG German National Licenses  (16)
  • Chemistry  (12)
  • DST  (2)
  • Organic acid disorders  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Affective Disorders 6 (1984), S. 265-272 
    ISSN: 0165-0327
    Keywords: Adolescence ; DST ; GH stimulation ; Major depressive disorder ; Puberty ; REM latency
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine , Psychology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Affective Disorders 6 (1984), S. 265-272 
    ISSN: 0165-0327
    Keywords: Adolescence ; DST ; GH stimulation ; Major depressive disorder ; Puberty ; REM latency
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine , Psychology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 153 (1994), S. S2 
    ISSN: 1432-1076
    Keywords: Inborn errors of metabolism ; Selective screening ; Treatment of inherited metabolic diseases ; Follow up of inherited metabolic diseases ; Organic acid disorders
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Selective screening for hereditary metabolic disorders has developed from a highly specialized activity, provided mostly by research oriented scientists, to an important diagnostic tool in the work-up of paediatric patients. A brief overview is given of the present status of selective screening in Europe, the USA and Israel including the distribution of centres and resources for diagnosis, therapy and follow-up. Current status and most pressing problems vary widely between different countries. Most countries still lack an organized network of clinical genetic centres which are capable of competent and comprehensive diagnostic and therapeutic services. For example, it must be assumed that more than 60% of patients with inherited metabolic diseases, which could be diagnosed nowadays, remain un(mis)diagnosed in former Western Germany. Early diagnosis and treatment are important determinants for a successful approach towards inherited metabolic diseases. Therefore, screening and therapy for inborn errors of metabolism has to be organized in clinical genetic centres, each serving a population between 2 and 4 million. The quality of the services provided depends on good pre-and postgraduate training of physicians (paediatricians) in the field of metabolic diseases, good co-operation between the referring physician and the clinical genetic centre and a broad spectrum of highly specialized metabolic investigations in the respective centre. The institutionalization has to include licensing of laboratories, directors and personnel, as well as quality control and proficiency testing. The size of the centres cannot be judged on the basis of the work involved with selective screening for inborn errors of metabolism alone. The number of diagnosed patients suffering from treatable metabolic disorders, such as those of amino or organic acid metabolism, are cumulative. The patients need lifelong dietary therapy, clinical assessment and biochemical monitoring.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 153 (1994), S. S94 
    ISSN: 1432-1076
    Keywords: Organic acid disorders ; Neurological symptoms ; Central nervous system ; Cerebrospinal fluid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Neurological manifestations are very common and can be the leading and/or presenting feature in organic acid disorders, sometimes in the absence of metabolic derangement. Review of the time course and presentation of neurological disease in organic acid disorders reveals characteristic clinical findings of ataxia, myoclonus, extrapyramidal symptoms, metabolic stroke and megalencephaly. A group of organic acid disorders presents exclusively with neurological symptoms. These include glutaryl-CoA dehydrogenase deficiency (glutaric aciduria type I), succinic semialdehyde dehydrogenase deficiency (4-hydroxybutyric aciduria), mevalonic aciduria,n-acetylaspartic aciduria (Canavan disease) andl-2-hydroxyglutaric aciduria. As a group these “cerebral” orgamic acid disorders appear to remain often undiagnosed and their true incidence is much less wellknown than that of the “classical” organic acid disorders. Unfortunately, stringent guidelines for a clinical preselection of neuropaediatric patients to be investigated for organic acid disorders cannot be provided. Today, screening for neurometabolic disorders should be as comprehensive as possible and include determinations of amino acids, purines and pyrimidines and markers of peroxisomal function in addition to organic acid analysis.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 334 (1992), S. 509-514 
    ISSN: 0941-1216
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The Influence of Sodium Polyvinylsulfate on the Photodimerization of Acridizinium PerchlorateDuring the irradiation of aqueous solutions of acridizinium perchlorate (λexc = 405 nm) a photodimer of this compound is formed. The quantum yield of the reaction depends on the concentration of the acridizinium ion. In 10-4 m solutions the quantum yield of dimerization is π = 0.0054 ± 0.0005. Addition of the anionic polyelectrolyte sodium polyvinylsulfate leads to a considerable increase of the quantum yield (up to π = 0.6) in dependence on the concentration of the polyion. A kinetic model is developed, including the electrostatic interaction of the acridizinium cation and the polyanion.The influence of diazonium cations as competitive agent is investigated and dicussed.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim [u.a.] : Wiley-Blackwell
    Materials and Corrosion/Werkstoffe und Korrosion 42 (1991), S. 467-472 
    ISSN: 0947-5117
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Influence of rust layers on corrosion reactions of low alloy steelsRust layers formed on iron base alloys are electrochemically highly reactive. Due to a polarisation of these oxide scales solid state reactions are induced, by which the 3-valent iron oxides are reduced. These redox reactions allow the dissolution of iron without the reduction of oxygen and therefore increase the corrosion rate, if the corrosion conditions vary periodically or if the material is coated by a polymer layer. Due to the oxide reduction electron-conducting oxides are formed, which determine the rate of the oxygen reduction. This causes the loss of adhesion for polymer coated and oxide covered iron substrates.
    Notes: Die auf Fe-Basislegierungen gebildeten Rostschichten sind elektronisch sehr reaktiv. Durch Polarisation dieser Oxidschichten werden Festkörperreaktionen ermöglicht, die zur Reduktion der 3-wertigen Oxidhydrate führen. Diese Redox-Reaktionen erlauben eine Eisenauflösung ohne Reduktion von Sauerstoff und erhöhen damit den Metallabtrag insbesonders bei periodisch variierenden Korrosionsbedingungen und bei polymerbeschichteten Werkstoffoberflächen. Durch die Oxidreduktion werden elektronenleitende Oxide gebildet, die die Kinetik von Sauerstoffreduktion bestimmen. Schließlich ändert sich bei der Reduktion der Rostschicht die Rostmorphologie. Dies führt zu einem Haftungsverlust bei polymerbeschichteten oxidbelegten Metalloberflächen.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 232 (1937), S. 61-74 
    ISSN: 0863-1786
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1. Calciumcarbid, welches gewöhnlich bei seiner technischen Gewinnung in flächenzentriert-tetragonalar Struktur (a = 5,48, c = 6,37 Å) (I) erhalten wird, bildet in Gegenwart von calciumeyanamid, seinem technisch wichtigsten Reaktionsprodukt, eine zweite, niedriger symmetrische Kristallart (II), welche bis etwa 15 Mol-% Cyanamid aufzunehmen vermag.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 558 (1988), S. 160-170 
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: On Some Properties and the Reactivity of Trichloroaluminium · Ethanthiol and Trichlorogallium · Ethanthiol ComplexesThe synthesis of aluminiumtrichloride · ethanthiol as well as galliumtrichloride · ethanthiol is given. The reactions of these 1:1-adducts with the Lewis bases N(CH3)3. P(CH3)3, O(C2H5)2 and S(CH3)2 and with the compounds (CH3)3SiSCH3 and Pb(SCH3)2 are discussed, the reaction products are investigated. Spectra as well as some chemical and physical properties of the starting material and the products are reported.
    Notes: Die Darstellung von Aluminiumtrichlorid · Ethanthiol bzw. Galliumtrichlorid · Ethanthiol wird beschrieben. Die Umsetzungen dieser 1:1-Addukte mit den Lewis-Basen N(CH3)3, P(CH3)3, O(C2H5)2 und S(CH3)2 sowie den Verbindungen (CH3)3SiSCH3 und Pb(SCH3)2 werden diskutiert, die Reaktionsprodukte werden untersucht. Spektroskopische Daten und einige chemische und physikalische Eigenschaften der Ausgangs- und Endprodukte werden mitgeteilt.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 620 (1994), S. 839-846 
    ISSN: 0044-2313
    Keywords: Chromium niobate ; chemical transport reactions ; block structure ; high resolution electron microscopy ; Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Contributions to the Investigation of Inorganic Non-Stoichiometric Compounds. XLIII. Preparation and Electron Microscopic Investigation of (Cr, Nb)12O29Transport experiments in the system Cr/Nb/O yielded the compound (Cr, Nb)12O29 as crystalline green needles. The lattice parameters of the monoclinic cell are a = 31.162(8) Å, b = 3.8324(6) Å, c = 20.579(6) Å, β = 113.22(3)°. (Cr, Nb)12O29 is isotypic with monoclinic Nb12O29 as shown by Guinier diagrams and high resolution transmission electron microscopy. Characteristic structural building elements are [3 × 4]-blocks which are columnar sections from the ReO3 structure. In the real structure one finds numerous defects. Under the influence of the electron beam we observed reversible changes of contrast which indicates that the positions of the M-particles (M = Cr, Nb) have shifted.
    Notes: Grüne, nadelförmige Kristalle von monoklinem (Cr, Nb)12O29 entstanden bei Transportexperimenten im System Cr/Nb/O. Die Gitterparameter a = 31,162(8) Å, b = 3,8324(6) Å, c = 20,579(6) Å, β = 113,22(3)° aus Guinieraufnahmen zeigen ebenso wie Strukturabbildungen mit der hochauflösenden Durchstrahlungselektronenmikroskopie Isotypie zu monoklinem Nb12O29. Auf den Aufnahmen erkennt man als charakteristisches Bauelement [3 × 4]-Blöcke, säulenförmige Ausschnitte aus der ReO3-Struktur, sowie zahlreiche Baufehler. Reversible Veränderungen des Kontrastes unter der Einwirkung des Elektronenstrahls lassen auf Änderungen der M-Positionen (M = Cr, Nb) schließen.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 452 (1979), S. 112-122 
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: On the Nucleophilic Degradation of Tris(pentasulfido)platinum(IV), [Pt(S5)3]2-, and Bis(pentasulfido)platinum(II), [Pt(S5)2]2-The behaviour of [Pt(S5)3]2-, (I), towards sulfite, arsenite, sulfide, hydroxide, and triphenylphosphine has been studied qualitatively and quantitatively. With stoichiometric amounts of nucleophile one ring is degraded; the reaction product [Pt(S5)2]2-, (II), can be isolated. With excess of nucleophile all sulfur atoms are taken off from the platinum; with triphenylphosphine, however, (PPh3)2PtS4, (III), is formed. A mechanistic interpretation of the course of the reaction is given and supported by kinetic studies.
    Notes: Das Verhalten von [Pt(S5)3]2-, (I), gegenüber Sulfit, Arsenit, Sulfid, Hydroxid und Triphenylphosphin wird qualitativ und quantitativ untersucht. Mit stöchiometrischen Mengen an Nukleophil wird ein Ring abgebaut; als Reaktionsprodukt kann [Pt(S5)2]2-, (II), isoliert werden. Mit Überschuß an Nukleophil werden alle Schwefelatome vom Platin abgelöst; mit Triphenylphosphin entsteht dagegen (PPh3)2PtS4, (III). Der Reaktionsablauf wird mechanistisch gedeutet und durch kinetische Untersuchungen erhärtet.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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