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  • Articles: DFG German National Licenses  (14)
  • Chemistry  (8)
  • Polymer and Materials Science  (8)
  • Rats  (4)
Source
  • Articles: DFG German National Licenses  (14)
Material
  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Mechanisms of Ageing and Development 31 (1985), S. 139-146 
    ISSN: 0047-6374
    Keywords: Aging ; Autofluorescence ; Lipofuscin ; Rats
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Mechanisms of Ageing and Development 33 (1985), S. 77-93 
    ISSN: 0047-6374
    Keywords: Aging ; Fine structure ; Lipofuscin ; Rats
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Mechanisms of Ageing and Development 31 (1985), S. 139-146 
    ISSN: 0047-6374
    Keywords: Aging ; Autofluorescence ; Lipofuscin ; Rats
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 4
    ISSN: 1432-0533
    Keywords: Key words Endothelial barrier antigen ; Blood-brain barrier ; Cerebral infarction ; Rats ; Angiogenesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Endothelial barrier antigen (EBA) can be used to detect the blood-brain barrier in the central nervous system of rats. This study investigated the temporal profile of antigen expression in cerebral vessels after infarction and assessed the relationship between re-establishment of this antigen in newly formed vessels and astrocytes around these vessels. Rats were subjected to cerebral ischemia for 2 h by the intraluminal thread method, then killed after 1, 3, 7, 14 and 28 days. Perfusion-fixed paraffin-embedded brains were immunostained for detection of EBA and glial fibrillary acidic protein (GFAP) by the streptavidin-biotin-peroxidase complex method. EBA immunostaining in vessels in the infarcted lesion was reduced at day 1 and had almost disappeared by day 3. Newly formed vessels were found from day 3, but were not stained at day 7. However, these new vessels were weakly stained at day 14 and definitely stained at day 28. GFAP immunostaining was completely negative around these proliferating vessels. The temporal profile of disappearance and re-expression of EBA in cerebral infarcted lesion may be associated with aggravation and improvement of brain edema, although barrier permeability was not explored in this study. The expression of this antigen has no relationship to the formation of astrocyte/endothelial contacts.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The conformation and packing scheme for guanosine-3′, 5′-cytidine monophosphate, GpC, were computed by minimizing the classical potential energy. The lowest energy conformation of the isolated molecule had dihedral angles in the range of helical RNA's and the sugar pucker was C3′ endo. This was used as the starting conformation in a packing search over orientation space, the dihedral angles being flexible in this step also. The packing search was restricted by constraints from our x-ray data, namely, (1) the dimensions of the monoclinic unit cell and its pseudo-C2 symmetry (the real space group is P21), (2) the location of the phosphorous atom, and (3) the orientation of the bases. In addition, a geometric function was devised to impose Watson-Crick base pairing. Thus, a trial structure could be sought without explicit inclusion of intermolecular potentials. An interactive computer graphics system was used for visualizing the calculated structures.The packing searches yielded two lowest energy schemes in which the molecules had the same conformation (similar to double-helical RNA) but different orientations within the unit cell. One of these was refined by standard x-ray methods to a discrepancy index of 14.4% in the C2 pseudocell. This served as the starting structure for the subsequent refinement in the real P21 cell.5
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The structural features of calcium guanosine-3′,5′-cytidine monophosphate (GpC) have been elucidated by X-ray diffraction analysis. The molecule was crystallized in space group P21 with cell constants of a = 21.224 Å, b = 34.207 Å, c = 9.327 Å, and β = 90.527°, Z = 8. The hydration of the crystal is 21% by weight with 72 water molecules in the unit cell. The four GpC molecules in the asymmetric unit occur as two Watson-Crick hydrogen-bonded dimers related by a pseudo-C face centering. Each dimer consists of two independent GpC molecules whose bases are hydrogen bonded to each other in the traditional Watson-Crick fashion. Each dimer possesses a pseudo twofold axis broken by a calcium ion and associated solvent.The four molecules are conformationally similar to helical RNA, but are not identical to it or to each other. Instead, values of conformational angles reflect the intrinsic flexibility of the molecule within the range of basic helical conformations. All eight bases are anti, sugars are all C3′-endo, and the C4′-C5′ bond rotations are gauche-gauche. The R factor is 12.6% for 2918 observed reflections at 1.2-Å resolution.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science Part A-2: Polymer Physics 8 (1970), S. 1195-1209 
    ISSN: 0449-2978
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The strain-optical coefficient and relaxation modulus were simultaneously measured for high-density polyethylene at various temperatures ranging from 12 to 100°C. Not only horizontal but also vertical shifts were necessary to obtain smooth master curves by the application of time-temperature superposition. However, the relaxation modulus decreases with rising temperature while the strain-optical coefficient increases. This behavior indicates that the variation of the relaxation modulus and the strain-optical coefficient with time can not be explained by a decrease in crystallinity with rising temperature since a decrease in crystallinity usually causes a decrease in the strain-optical coefficient with time can not be explained by a decrease in crystallinity with rising temperature since a decrease in crystallinity usually causes a decrease in the strain-optical coefficient. It was emphasized that another explanation should be sought for the vertical shift in the time-temperature superposition of the time-dependence curves of the relaxation modulus and the strain-optical coefficient at various temperatures. The master curve of the strain-optical coefficient at various temperatures. The master curve of the strain-optical coefficient or the optical distribution function of relaxation times determined from it serve to distinguish the type and thermal history of the polyethylene.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 26 (1988), S. 2839-2847 
    ISSN: 0887-624X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Journal of Polymer Science Part A-2: Polymer Physics 8 (1970), S. 1211-1225 
    ISSN: 0449-2978
    Keywords: Physics ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: To determine the true reason for the increase in birefringence and the decrease in relaxation modulus for high-density polyethylene with rising temperature, changes in crystalline structure as well as in thermal, viscoelastic, and rheo-optical properties with temperature were measured, by several techniques, including DSC, DLI, infrared dichroism, x-ray diffraction, and NMR. The values for degree of crystallinity obtained from the DSC fusion curve, density, and infrared absorbances coincide very well and show almost no divergence till about 80°C. The optical vertical shift factor pT can be related to the ratio of the orientation function for the crystal c axis at an arbitrary temperature to that at the references temperature, fε/fε0. The mechanical vertical shift factor bT, on the other hand, is associated with the temperature dependence of the mobile fraction, as determined by NMR measurements, but not with variations in degree of crystallinity.
    Additional Material: 17 Ill.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 0142-2421
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: In Auger electron spectroscopy, the relative sensitivities of elements, which are widely used in quantitative analysis, are primarily obtained by measurement. Nevertheless, it is very tedious to collect all relative elemental sensitivity factors for different primary electron beam energies. In view of this, we have examined methods of deriving the relative sensitivity factor for an arbitrary electron beam energy from one experimental value determined at a set energy. For this calculation, we have to consider the contributions of the ionization cross-section and the electron backscattering factor. Several formulas for the ionization cross-section and the backscattering correction factor have been reported. We have performed experiments to examine their correction accuracy. It was found that when Gryziński's formula is used as the ionization cross-section and Love-Scott's formula as the backscattering correction factor, the difference between calculated sensitivity values and measured values was found to be 〈15% for excitation energies of 〈20 keV.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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