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  • Articles: DFG German National Licenses  (2)
  • Chemotherapy  (1)
  • Dopplersonographie  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 109 (1985), S. 210-216 
    ISSN: 1432-1335
    Keywords: Gynecological tumors ; In vitro proliferation assay ; Individual chemosensitivity ; Chemotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cell lines established from advanced mammary and ovarian carcinomas were assayed for the inhibition of in vitro proliferation by various antineoplastic drugs. The assays were performed with multiple experimental cultures derived from stock cultures of the tumor cell lines in early passages of the cultivation. As determined by comparison of the 50% inhibition of in vitro growth, differential sensitivity of the individual cell lines was observed. Based on the 2-h plasma level of the drugs as discriminatory threshold between resistance and sensitivity, the in vitro effectiveness of each, drug on the individual cell lines was compared with the clinical results of chemotherapy applied to the corresponding patients. In total, positive in vitro/in vivo correlations were observed in 39 of 42 cases. The 17 cell lines evaluated retrospectively were resistant to those drugs which had been tried unsuccessfully during chemotherapy. Among the 25 cases tried prospectively 11 cases showed sensitivity in vitro and in vivo, and furthermore 11 prospective cases were resistant in vitro and in vivo.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2102
    Keywords: Schlüsselwörter High-flow-Priapismus ; Perineales Trauma ; Superselektive Embolisation ; Dopplersonographie ; Angiographie ; Key words High-flow priapism ; Perineal trauma ; Superselective embolization ; Dopplerultrasound ; Angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A 10-year old boy developed an arteriocavernosal fistula with a permanent penile erection (high-flow priapism) after a blunt perineal trauma. The diagnosis was established by Doppler ultrasound, blood gas analysis and angiography. A conservative treatment attempt with penile cooling and puncture of the cavernosal corpera with blood aspiration and etilefrine instillation failed to resolve the priapism. An embolization of both bulbocavernosal arteries was followed by an immediate detumescence. Normal functional erection was preserved. No recurrence was observed during a follow-up of 6 months.
    Notes: Zusammenfassung Bei einem 10jährigen Jungen kam es nach einem stumpfen perinealen Trauma zu einer Dauererektion durch eine arteriokavernöse Fistel (High-flow-Priapismus), die durch Doppler-Sonographie, Blutgasanalyse und Angiographie nachgewiesen wurde. Nach Versagen einer Behandlung mit Kühlung, Dekompression der Corpora cavernosa durch Punktion und Etilefrin-Instillationen wurde eine endovasale Verschlußbehandlung der die Fistel speisenden Aa. bulbourethrales mit Mikrocoils vorgenommen. Die Behandlung führte zu einer sofortigen Detumeszenz bei erhaltener Erektionsfähigkeit. Während einer Nachbeobachtungszeit von 6 Monaten trat kein Rezidiv des Priapismus auf.
    Type of Medium: Electronic Resource
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