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  • Articles: DFG German National Licenses  (2)
  • DNA flow cytometry  (2)
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  • Articles: DFG German National Licenses  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Effects of epidermal growth factor, fibroblast growth factor, minoxidil and hydrocortisone on growth kinetics in human hair bulb papilla cells and root sheath fibroblasts cultured in vitro (1987)
    Springer
    Archives of dermatological research 279 (1987), S. 247-250 
    Details
    ISSN: 1432-069X
    Keywords: Hair bulb papilla cells ; Hair root sheath fibroblasts ; Proliferation in vitro ; DNA flow cytometry ; Effect of different pharmacological agents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Comparative studies on growth kinetics of cultivated human hair bulb papilla cells (PCs) and hair root sheath fibroblasts (RSFs) yielded evidence of some pecularities of PCs in both proliferative behavior and morphological growth pattern. As the dermal papilla, essentially supporting the nutrition of matrix epithelium, can be considered a target tissue for agents influencing maintenance of hair growth, we studied the effects of epidermal growth factor (EGF), fibroblasts growth factor (FGF), minoxidil (Mino), and hydrocortisone (HC) on the proliferation of PCs and RSFs, both gained from dissected hair follicles of scalp biopsy specimens of two male adults and separately cultured in vitro. EGF and FGF proved to increase proliferation of both PCs and RSFs most, yet at a different intensity for each cell group. HC slowed proliferation, and Mino failed to influence growth of PCs and RSFs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00417323
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Comparative morphological and growth kinetics studies of human hair bulb papilla cells and root sheath fibroblasts in vitro (1986)
    Springer
    Archives of dermatological research 279 (1986), S. 20-25 
    Details
    ISSN: 1432-069X
    Keywords: Hair bulb papilla cells ; Root sheath fibroblasts ; Cell culture ; Growth pattern ; DNA flow cytometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Dermal papillae isolated from anagen hair bulbs obtained from biopsy specimens from five subjects with normal hair pattern, and fibroblasts derived from the mesenchymal root sheaths (RSF) of the same hair follicles were separately grown in culture and the cellcycle distribution pattern on different days was analysed by applying DNA flow cytometry (FCM). Papilla cells (PC) exhibited distinctive morphological features by forming cell aggregates differing from RSF with respect to cell shape and growth pattern. They also proliferated remarkably more slowly than RSF. DNA-FCM analysis showed that both PC and RSF demonstrated synchronous fluctuations in the percentage of cells in G1/0, S and G2+M phases during the period of subculture.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00404353
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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