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  • Artikel: DFG Deutsche Nationallizenzen  (5)
  • FT-IR  (3)
  • Enhanced-sensitivity NMR  (1)
  • Heart  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Immunohistochemical localization of mitogen-activated protein kinase (MAPK) family and morphological changes in rat heart after ischemia-reperfusion injury (2000)
    Springer
    Medical electron microscopy 33 (2000), S. 74-81 
    Details
    ISSN: 1437-773X
    Schlagwort(e): Key words Mitogen-activated protein kinase (MAPK) ; Ischemia reperfusion injury ; Heart ; Ultrastructure ; Immunohistochemistry
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The mitogen-activated protein kinase (MAPK) family is considered to be activated by stress, but the role of the MAPK family is still unknown in cardiac pathology. In the present study, not only the localization of MAPKs such as the extracellular responsive kinase (ERK), c-jun N-terminal kinase (JNK), and p38 MAPK (p38), but also ultrastructural changes were investigated in the ischemia-reperfusion model of Wistar rats. At 5, 10, 30, 60, and 180 min reperfusion after 30 min ischemia by occluding the coronary artery, the expression of these MAPKs was increased in blood vessels and cardiomyocytes by Western blotting and immunohistochemical methods. In addition, after ischemia reperfusion, various ultrastructural changes such as decreased glycogen granules, mitochondrial swelling, and myolysis were observed in the blood vessels and cardiomyocytes. These results suggest that protein kinases may regulate numerous biological processes, including the regulation of contraction and ion transport.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s007950070005
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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    Artikel (Nationallizenzen)
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  • 2
    Digitale Medien
    Digitale Medien
    Fourier transform infrared study on the hydration of polycytidylic acid (poly C) (1988)
    Springer
    Microchimica acta 94 (1988), S. 365-368 
    Details
    ISSN: 1436-5073
    Schlagwort(e): polycytidylic acid (poly C) ; hydration ; FT-IR
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Abstract The Fourier transform infrared spectra and subtraction spectra of poly C film in the 4000 to 800 cm−1 region at 22°C were measured systematically as a function of relative humidity (from 0% to 100%) at static equilibrium. The peak position and intensity changes of infrared bands prove that the hydration of poly C has happened mainly on the-NH2 and C=O group of cytidine base, phosphate and ribose ring. The ~1664 cm−1 peak (NH2) and the ~1655 cm−1 peak (C=O) show the strongest variation in intensity starting from R.H. 〈12%. In comparison with the hydration of poly A which we studied, it indicates: (1) The polynucleotide molecules are surrounded by hydration water at their active sites. (2) Poly C can more easily be hydrated than poly A, since the polar group C=O of cytidine plays an important role during hydration.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01205908
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    FT-IR photoacoustic spectra of the surface of Ru3(CO)12/Al2O3 system (1988)
    Springer
    Microchimica acta 95 (1988), S. 171-174 
    Details
    ISSN: 1436-5073
    Schlagwort(e): FT-IR ; photoacoustic spectra (PA) ; surface ; PA spectra of Ru3(CO)12/Al2O3
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Abstract The FT-IR photoacoustic spectra of Ru3(CO)12/Al2O3 (acidic and basic alumina) system have been measured for different ageing times. The behaviors of oxidation states of Ru on the surface of basic or acidic alumina and their difference are discussed on the ground of CO stretching bands of their spectra.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01349746
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    FT-IR study and normal vibration analysis of rare earth oxalates (1988)
    Springer
    Microchimica acta 94 (1988), S. 235-238 
    Details
    ISSN: 1436-5073
    Schlagwort(e): FT-IR ; normal vibration analysis ; rare earth oxalates ; IR spectra
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Abstract In the present investigation, four rare earth oxalates with different electronic structure [f 0(La, Y),f 7(Gd) andf 14(Lu)] were prepared. Their Fourier transform far- and mid-infrared spectra were examined with a Nicolet 7199 B spectrometer in a range from 100–4000 cm−1. Normal vibrational analysis of La, Gd, Lu and Y oxalate hydrates were carried out according to the FT-IR results. The assignment of vibrational frequencies is made on the basis of normal coordinate analysis. The average deviations of 30 frequencies of the four oxalates between the calculated and the experimental values are La=4.49, Gd=4.04, Lu=4.63 and Y=4.98 cm−1, respectively.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01205878
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    An enhanced-sensitivity pure absorption gradient 4D 15N, 13C-edited NOESY experiment (1993)
    Springer
    Journal of biomolecular NMR 3 (1993), S. 463-470 
    Details
    ISSN: 1573-5001
    Schlagwort(e): Pulsed field gradients ; Enhanced-sensitivity NMR ; Four-dimensional NOESY
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Summary An enhanced-sensitivity gradient 4D 15N, 13C-edited NOESY experiment is presented. Gradients are employed to suppress artifacts, eliminate the intense H2O signal and select for the coherence transfer pathway involving 15N magnetization. The latter use of the gradients results in a decrease in the number of phase cycle steps by a factor of two relative to the previously published 4D sequence (Kay et al., 1990) allowing for the recording of spectra with increased resolution per unit measuring time. Theoretical sensitivity enhancements of as much as a factor of $$\sqrt 2 $$ can be expected over the previously published sequence, neglecting the effects of relaxation and pulse imperfections.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00176011
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